Drug design, with particular expertise in effective peptide-based drugs, medicinal chemistry, and technological synergies
1. Pharmacognosy and natural products chemistry
2. Biocatalysis
3. Combinatorial chemistry/parallel synthesis techniques
4. Microwave assisted organic synthesis
5. Solid-phase organic synthesis
6. Computational chemistry
Business aspects of drug discovery companies (large and small)
1. Operations
2. Leadership/management
3. Funding/partnering
John L. Krstenansky, Jihong Wang, Gregg R. Chenail, Matthew R. Tiffany, Geoffrey M. Kuesters, Barbara C. Natke, John J. Nestor, Jr, Probing Proteinase Active Sites Using Oriented Peptide Mixture Libraries-ADAM-10, Letters in Drug Design and Discovery, 1(1), 6-13, January 2004
John L. Krstenansky and Peter C. Michels, The state of combinatorial solution-phase research: Combinatorial biocatalysis. In: Carmen M Baldino, Perspective Articles on the utility and application of solution-phase combinatorial chemistry, Journal of Combinatorial Chemistry, 2(2), 89-103, 2000
John L. Krstenansky and Ian Cotterill, Recent advances in microwave-assisted organic synthesis, Current Opinion Drug Discovery and Development, 3(4), 454-461, 2000
Krstenansky JL, Khmelnitsky Y, Biocatalytic combinatorial synthesis, Bioorganic and Medicinal Chemistry, 7(10), 2157-62, October 1999
Hemmerich S, Paavola C, Bloom A, Bhakta S, Freedman R, Grunberger D, Krstenansky J, Lee S, McCarley D, Mulkins M, Wong B, Pease J, Mizoue L, Mirzadegan T, Polsky I, Thompson K, Handel TM, Jarnagin K, Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2, Biochemistry, 38(40), 13013-25, October 1999
American Association of Colleges of Pharmacy
American Chemical Society
American Society of Pharmacognosy
European Peptide Society
New York Academy of Sciences
RXPS 611 Medicinal Chemistry I
RXPS 612 Medicinal Chemistry II
RXPS 613 Medicinal Chemistry III
Last Revised: Mon, Feb 25, 2008
