Division of anatomy

Faculty - Michael A. Kirby, PhD

Personal statement | Research

Address
Loma Linda University Medical Center
Department of Pediatrics
11262 Campus Street
Loma Linda, CA 92350

Phone: (909) 558-1000, extension 42274

Education

1978 BS, physiological psychology (minor, chemistry), Arizona State University, Tempe, AZ

1980 MA, physiological psychology, California State University, Sacramento, CA

Thesis: "Extracellular recording in the cingulate cortex of the rat. Influence of the estrus cycle."

1984 (December) PhD, neuroscience, University of California, Riverside, CA Dissertation: "Receptive field properties of cells in the lateral geniculate nucleus of the North American opossum (Didelphis virginiana)."

Fellowships

1985-1987 Individual postdoctoral fellowship, NIH (National Eye Institute)-
Developmental Neurobiology, University of California, Davis, CA

Honors

Arizona State University Academic Scholarship (1974-1978)
Dean's List - Arizona State University (1974-1978)
Arizona State University Music Scholarship (1974-1978)

Research interests
Neuroscience (neurophysiology and neuroanatomy) with special concentration in developmental neurobiology.

Current projects

• The ontogeny of cell class in the monkey retina.
• The centro-peripheral gradient of retinal ganglion cell maturation in the fetal monkey.
• Genetic determinants of ganglion cell proliferation.
• Morphogenesis of retinal ganglion cells during formation of the fovea in the rhesus macaque.
• Effects of microbeam proton irradiation on the LGN of the cat central nervous system.
• Effects of microbeam proton irradiation on the developing central nervous system of the cat.
• Functional and structural reorganization of the cat's retinocollicular projection following fetal enucleation.
  
• Morphological maturation of horizontal cells in the retina of fetal rhesus monkey.
• Photoreceptor distribution in the retina of the baboon.
• Topographic organization of the retinocollicular projections in the fetal cat.
• Functional reorganization of the primate fovea following cortical destruction.

Society memberships

• American Association for the Advancement of Science (1979-present)
• The Society for Neuroscience (1983-present)
• Association for Research in Vision and Ophthalmology (1985-present)
• Hinterland Pediatric Society (1987-present)
• The Western Society for Pediatric Research (1989-present)
• The New York Academy of Sciences (1990-present)
• The J.B. Johnston Club (1990-present)
• Associate Member American Museum of Natural History (1991-present)

Appointments

1978-80 Research assistant
Neurophysiology/Neuroanatomy, California State University, Sacramento

1980-84 Research associate
Neurophysiology/Neuroanatomy, University of California, Riverside

1980-84 Visiting lecturer
Chaffey Community College

1983-84 Electron microscopist 1
Department of Biology, University of California, Riverside

1985-87 Individual postdoctoral fellow
National Eye Institute, NIH, University of California, Davis

1985-87 Lecturer
University of California, Davis

1987-91 Assistant professor
Departments of Pediatrics and Anatomy and Division of Perinatal Biology
Loma Linda University, Loma Linda

1992 Associate professor
Department of Pediatrics and Anatomy and the Center for Perinatal Research
Loma Linda University, Loma Linda

1993 Associate chair (research), Department of Pediatrics, Loma Linda University, Loma Linda

1994 Associate professor department of pathology and human anatomy, Loma Linda University

1997-98 Visiting associate professor (sabbatical), Department of Biological Structure, University of Washington, Seattle

2001 Chair, animal research committee (IACUC)

2002 Member of the School of Dentistry Academic Review Committee

2002 Member of the School of Medicine Academic Review Committee

Grants

1980-83 Regent's Research Grant - University of California
Research Grant $800.00. "Development of the mammalian optic nerve."

1985-87 Individual Postdoctoral Fellowship - NIH, National Eye Institute, $97,000.00 "Prenatal development of the cat's visual system."

1987 Loma Linda University Seed Money Grant, $6,300.00 "Prenatal development of primate retinal ganglion cells."

1988 NIH Small Equipment Money, $9,300.00 "Prenatal development of primate retinal ganglion cells."

1988 NIH Shared Equipment Grant $115,000.00 (co-investigator)

1989 Fight For Sight Award. Fight For Sight Foundation, New York, N.Y. $1,200.00 (summer fellowship award)

1990 Basic Science/Student-Faculty Research Award. The Walter E. Macpherson Society
$500.00

1991 Society for Pediatric Research $1,200.00 (summer fellowship program)

1992 BRSG Grant $7,000.00 "Effects of proton beam irradiation on developing neural tissue."

1992 Association for Research in Vision and Ophthalmology (ARVO)
Travel Grant (graduate student) $2,000.00, Bethesda, MD

1992 Pediatric Seed Money Grant $8,000.00 "Effects of microbeam proton irradiation on developing neural tissue."

1993 NIH-BRSG Grant $9,028.00 "Small Instruments Grant."

1994 Sigma Xi Grant - $3,500.00

1996 Pediatric Seed Money Grant $20,000.00 (Co-P.I.) "Effects of microbeam proton irradiation on neural tissue in vitro."

1996 BSRG Grant-$4,000.00-Development of the primate fovea following monocular enucleation.

1996 NIMH Summer Medical Student Research Grant (Minorities) $3,800.00

1996 NASA "A Multi-Institutional NSCORT Consortium in Radiation Health" (Jim Slater, M.D., P.I.-Loma Linda University), John DiCelo, Ph.D., Overall P.I.-Johns Hopkins University.

1996 Michael and Helen Schaffer Foundation. $14,000.00 Effects of Proton Beam on Developing Neural Tissue

1997 American Pediatric Society/Society for Pediatric Research, Summer Research Program, $2,000.00.

1998 National Medical Technology Testbed. Genetic control of retinal ganglion cell differentiation. $15,000.00

1999 Stint Fellowship Program (Swedish Government Funding). "Using Biochemical, Tribological, Cell Biology and Clinical Experiments to Develop International Standards For Hip and Knee Prostheses." $383,000.00 (Co-P.I.).

2000-2003 National Medical Technology Testbed. FGF-15 and FGF8 determine retinal ganglion cell fate in the developing retina. $98,000.00/year.

2000 Neuroimmune Mechanisms for Parturition (BSRG). Co-P.I., $10,000.00

2000 Neuroimmune and Macrophage Mechanisms for Parturition (VA Grant). Co-P.I. $20,000.00

2000 Hyperinnervation of the Striatum of Adult Rats (BSRG). Co-P.I. $9,726.00.

2001 The role of neurotrophic factors in the proliferation of osteoblasts. The John Mace Pediatric Foundation. P.I. $28,000.

2002 The Localization and Quantification of Fibroblast Growth Factors and Receptors within the Developing Retina. The John Mace Pediatric Foundation. P.I. $15,850.00.

2002 Neuroimmune Mechanisms for Parturition. Co-P.I. (NIH) $1,539,440 (pending).

Publications

M.A. Kirby (2003) The Brain Atlas. J. of Neurosurgery, In Press.

Dean M. Murakami, Michael A. Kirby, Charles A. Fuller, and David H. Rapaport, 2003. Entrainment of circadian rhythms is lost in a mouse mutant (Brn3.2 -/-) which retains only a fraction of the normal complement of retinal ganglion cells. Submitted.

M.A. Kirby (2002). Probabilistic Models of the Brain. J. of Neurosurgery, In press.

M.A. Kirby (2002) Cerefy Brain Atlas. J. of Neurosurgery, In Press.

M.A. Kirby, and D.H. Rapaport (2001). Human Neuroanatomy. J. of Neurosurgery, 95:912-913..

Allan, G., Liu, J-W, Kirby, M.A., and M. DeLeon. 2001. Induction and axonal localization of E-FABP in retinal ganglion cells is associated with axon regeneration. J. Neuroscience Research, 66:396-405.

Christensen, D.W., Kisling, R., Thompson, J., and M.A. Kirby, 2001. Deferoxamine Toxicity in Hepatoma and Primary Rat Brain Cultures. Human and Experimental Toxicology, 20:1-12.

Erkman, L., P.A. Yates, T. McLaughlin, R.J. McEvilly, T. Whisenhunt, S.M. O'Connell, A.I. Krones, M.A. Kirby, D.H. Rapaport, J.R. Bermingham, D.D.M. O'Leary, & M.G. Rosenfield, 2000. Cell autonomous regulation of axon pathfinding in the vertebrate visual system by a Brn-3.2 dependent transcriptional program. Neuron, 28:779-792.

Reder, C.S., M. Moyers, and M.A. Kirby, 2000. Physiological Alteration of CNS cells following Proton Irradiation, International Journal of Radiation Oncology, Biology, and Physics, 46:1247-1257.

M.F. Moyers, R.A. Galindo, L.T. Yonemoto, L. Loredo, E.J. Friedrichsen, M.A. Kirby, J.D. Slater, and J.M. Slater, 1999. Treatment of macular degeneration with proton beams. Medical Physics, 26:777-782.

Distler, C., and M.A. Kirby, 1996. Astrocytes in the newborn macaque monkey retina, European Journal of Neuroscience, 8:847-851.

Chalupa, L.M. , C.J. Snider, and M.A. Kirby, 1996. Topographic organization in the retinocollicular pathway of the fetal cat demonstrated by retrograde labeling, Journal of Comparative Neurology, 368:295-303.

Kirby, M.A. and Steineke, T.C., 1996. Morphogenesis of retinal ganglion cells: implications for foveal development, Perspectives on Developmental Neurobiology, 3:177-194.

Yellon, S.M., K.J. Thorn, K.L. Buchanan, and M.A. Kirby, 1993. Retinal input of the suprachiasmatic nucleus before and after puberty in Djungarian hamsters. Brain Research Bulletin, 32:29-33.

Steineke, T.C., and M.A. Kirby, 1993. Early axon outgrowth of retinal ganglion cells in the fetal rhesus monkey. Developmental Brain Research, 74:151-162.

Kirby, M.A., and Steineke, T. 1992. Morphogenesis of retinal ganglion cells during formation of the fovea in the rhesus macaque. Visual Neuroscience, 9:603-616.

Kirby, M.A., and Steineke, T.C., 1991. Early dendritic outgrowth of primate retinal ganglion cells. Visual Neuroscience, 7:513-530.

Fischer, Q.S. and Kirby, M.A., 1991. The number and distribution of retinal ganglion cells in the adult baboon (Papio anubis). Brain, Behavior and Evolution, 37:189-203.

Yhip, J.P., and Kirby, M.A., 1990. Topographic Organization of the Retinocollicular Projection in the Neonatal Rat. Visual Neuroscience, 4:313-329.

Miller, S., and Kirby, M.A., 1990. Freidreick Tiedemann in S. Ashwell (Ed.), The Founders Of Child Neurology. Norman Publishing; San Francisco.

White, C.A., L.M. Chalupa, L. Mafei, M.A. Kirby and B. Lia. 1989. Response properties in the dorsal lateral geniculate nucleus of the adult cat after interruption of prenatal binocular interaction. Journal of Neurophysiology, 62: 1039-1051.

Kirby, M.A., T. Parker and P.D. Wilson, 1988. Axon addition and attrition in the developing optic nerve. Developmental Brain Research, 44:37-48

Kirby, M.A., and P.D. Wilson, 1986. Receptive field properties and latencies of cells in the lateral geniculate nucleus of the North American opossum. Journal of Neurophysiology, 56:907-933.

Kirby, M.A., and L.M. Chalupa, 1986. Retinal crowding alters the morphology of alpha ganglion cells. Journal of Comparative Neurology, 251:532-542.

Kirby, M.A., L. Clift-Forsberg, P.D. Wilson and S.C. Rapsardi, 1982. Quantitative analysis of the optic nerve of the North American opossum (Didelphis virginiana): An electronmicroscopic study. Journal of Comparative Neurology, 211:318-327.

Kirby, M.A., 1984. Receptive field properties of cells in the lateral geniculate nucleus of the North American opossum (Didelphis virginiana). Doctoral Dissertation, University of California, Riverside, California.

Kirby, M.A., 1980. Extracellular recordings in the cingulate cortex of the rat: Influence of the estrous cycle. Masters Thesis, California State University, Sacramento, California.

Abstracts

Pender, R, and M.A. Kirby (2002) The role of FGF-15 and FGF receptors during retinal ganglion cell genesis. IV Ophthamology (IPO) Congress of China. Shantou, China. June 29, 2002.

M.A. Kirby (2001) A Tale of Two Genes. International Ophthalmology and Visual Neuroscience Meeting (INOVS). Sydney, Australia, July 25, 2001.

Kirby, L.S., M.A. Kirby, and S.M. Yellon 2001 Increased neural innervation of the cervix precedes parturition in the mouse. Soc. Neurosci., 27: In Press.

M.A. Kirby, G.W. Allan, M. DeLeon. 2001. E-FABP expression in the developing retina is expressed only in retinal ganglion cells. Investigative Ophthalomology and Visual Science, 42:S354.

KS Rau, MA Kirby, J Buchholz, RP Iacono, and G Maeda. Striatal dopamine release by serotonergic terminals in the dopamine depleted rat. Exper. Biology, Orlando, FL. April 2001.

KS Rau, MA Kirby, J Buchholz, RP Iacono, and G Maeda, 2000. Striatal utilization of L-dopa in dopamine depleted rats requires serotonin neurons. Soc. Neurosci. 27:835.

G.W. Allen, J. Liu, M.A. Kirby, M. De Leon. 2000. E-FABP Expression and localization in developing rat retina and dissociated retinal culture. Soc. Neurosci 26: 1384.

M.A. Kirby, K. McCabe, J. McWhirter, and T. Reh. 2000. Retinal ganglion cell differentiation in the fetal rat is influenced by FGF-15. Investigative Ophthalomology and Visual Science, 39:S870.

M.A. Kirby, K. McCabe, J. McWhirter, and T. Reh. 1999. FGF-15 influences retinal ganglion cell differentiation in the rat. Soc. Neuroscience 25: 2265.

M.A. Kirby, D.M. Murikami, L. Erkman, M.G. Rosenfeld, and D. H. Rapaport 1997 Effect of brain 3.2 deletion on ganglion cell morphology. Investigative Ophthalomology and Visual Science, 38:S924.

Snyder, M.D., and Kirby, M.A. 1996. Dendritic development of putative blue ganglion cells in the rhesus macaque. Soc. Neuroscience 22:1203.

Mohamed, AS, Iacono, RP, JC Wu, J. Carlson, S. Kuniyoshi, MA Kirby. Pet evidence of posterior ansa pallidotomy as a postsynaptic modulator of basal ganglia function in Parkinsonian patients. Soc. Neuroscience 23:658.

Y. Lui, C.A. Molina, M. Kirby, L.D. Longo, and M. DeLeon 1996. Comparison of the expression of a novel FABP in developing and adult rat central nervous system. Soc. Neuroscience 22:1019.

M.F. Moyers, R. Galindo, L. Yonemoto, L. Loredo, E Friedrichsen, M. Kirby, and J.D. Slater 1996. Treatment of SNVMS with proton beams. A.A.P.M..

Q.S. Fischer, Wilson, P.D., and M.A. Kirby 1996. Retinocollicular topography in normal and monocular enucleate North American Opossums. Investigative Ophthalomology and Visual Science, 37:S4946.

M. Kirby, and C. Distler 1995. GFAP positive cells in the developing retina avoid the fovea. Investigative Ophthalomology and Visual Science, 36:S647.

Mackler, A.M., Kirby, M.A., and S.M. Yellon 1995. GnRH neurons and photorefractoriness in the male Djungarian hamster. Soc. Neuroscience 21:100.

C. Distler, and M.A. Kirby 1994. Astrocytes in the developing macaque monkey retina. Soc. Neuroscience 20:1070.
M. Kirby 1994. Mechanisms of foveal development in the rhesus monkey. 2nd International meeting on Brain Transplantation and Regeneration. Singapore Neuroscience Society, 2, 87.

D. Xie, R. Schultz, E. Whitter, P. McMillian, and M.A. Kirby, 1994. The oligodendrocyte reaction and reactive glosis after stab wounds to rat brain. Soc. Neurosc. Abstr. 20:884.

T.C. Steineke, S.M. Yellon, and M.A. Kirby, 1993. The role of bistratified cells in the establishment of retinal mosaics in the fetal rhesus macaque. Soc. Neurosc. Abstr. 19:54.

Q.S. Fischer, P.D. Wilson, and M.A. Kirby, 1993. Retinocollicular topography following monocular enucleation in the North American opossum. Soc. Neurosc. Abstr. 19:453.

K.L. Buchanan, V.L. Jennings, and M.A. Kirby., 1993. Measurement of foveal area in the rhesus monkey during fetal development. Soc. Neurosc. Abstr. 19:54.

D.C. Lau, C.S. Reder, S.J. Ashwal, and M.A. Kirby, 1993. Short-term effects of proton microbeam irradiation on feline LGN. Soc. Neurosc. Abstr. 19: 1072.

Kim, S.J., and Kirby, M.A., 1992. Prenatal development of horizontal cells in the retina of the rhesus monkey. Soc. Neurosc. Abstr. 18:1318..

Fischer, Q., Kirby, M.A., Jennings, V., and Mielke, J., 1992. Photoreceptor topography in the retinae of anubis baboons. Soc. Neurosc. Abstr. 18:838.

Steineke, T.C., Fischer, Q.S., Wilson, P.D., and Kirby, M.A., 1992. Reorganization of retinocollicular topography following fetal enucleation in the cat. Soc. Neurosc. Abstr. 18:1312.

Steineke, T.C., and Kirby, M.A., 1992. Axon trajectory of developing retinal ganglion cells in the fetal rhesus monkey. Soc. Ped. Res. 40:41A

Steineke, T.C., and Kirby, M.A., 1992. Morphogenesis of retinal ganglion cells during formation of the fovea in the rhesus macaque. Soc. Ped Res. 40:109A

Fischer, Q.S., Wilson, P.D., Steineke, T.C., and Kirby, M.A., 1992. Retinocollicular topography in normal and fetal enucleate cats. Invest. Ophthal. and Vis. Sci. Abstr. 33:1059.

Kim, S.J., and Kirby, M.A., 1992. Morphological development of horizontal cells in the retina of the fetal rhesus macaque. Invest. Ophthal. and Vis. Sci. 33:1060

Steineke, T.C., and Kirby, M.A., 1992. Axon trajectory of developing retinal ganglion cells in the fetal rhesus monkey. Soc. Ped. Res. 40:41A

Steineke, T.C., and Kirby, M.A., 1992. Morphogenesis of retinal ganglion cells during formation of the fovea in the rhesus macaque. Soc. Ped Res. 40:109A

Kirby, M.A., and Steineke, T.C., 1991. Evidence for the radial migration of retinal ganglion cells during formation of the fovea. International Brain Research 3:315.

K.L. Buchanan, M.A. Kirby, and S.M. Yellon, 1991. A study of GnRH neurons that project to the medial basal hypothalamus in the male djungarian hampster. Soc. Neurosci. Abstr. 17:971.

Kirby, M.A., and T.C. Steineke, 1991. Evidence for the radial migration of retinal ganglion cells during formation of the fovea. Invest. Ophthal. and Vis. Sci. 32:1130.

Kirby, M.A., 1990. Dendritic stratification of primate retinal ganglion cells during fetal development. Invest Ophthal. and Vis. Sci. 31:274.

Richburg, F.A, and M.A. Kirby, 1990. Topographic development of the corticocollicular projection in the neonatal rat. Clinical Review 39:104A.

Steineke, T.C., and M.A. Kirby, 1989. Early axon outgrowth of retinal ganglion cells in the retina of the rhesus macaque. Invest. Ophthal. and Vis. Sci. 30: 226.

Richburg, F.A., and Kirby, M.A. 1989. Development of the corticotectal projection in the neonatal rat. Soc. Neurosci. Abstr. 15: 1337.

Yhip, P.J.A. and M.A. Kirby, 1988. Is there substantial topographic order during development of the rat retinocollicular projection? Soc. Neurosci. Abstr. 14:675.

Fischer, Q., P.D. Wilson and M.A. Kirby, 1988. Topographic organization of the ganglion cell layer of the adult baboon (Papio anubis). Soc. Neurosci. Abstr. 14:1119.

DeJager, D. and M.A. Kirby, 1988. Morphological development of primate retinal ganglion cells. Soc. Neurosci. Abstr. 14:458.

Kirby, M.A., 1988. Dendritic maturation of primate retinal ganglion cells. Proc. Int'l. Symp. Retinal Development and & Regeneration. 1:21.

Fischer, T.M., M.A. Kirby and P.D. Wilson, 1988. Development of the inner plexiform layer of the North American opossum. Soc. Neurosci. Abstr. 14:673.

Kirby, M.A., Lia, B., and Chalupa, M.L., 1988. Retino-retinal projections in the fetal cat. Invest. Ophthal. and Vis. Sci. 29:206.

Lia, B., Kirby, M.A., and Chalupa, L.M., 1987. Decussation of retinal ganglion cell projections during prenatal development of the cat. Soc. Neurosc. Abstr. 13:1690.

White, C.H., Kirby, M.A., Chalupa, M.L., Maffei, L., Lia, B., 1987. Functional consequences of prenatal enucleation in the dorsal lateral geniculate nucleus of the cat. Soc. Neurosc. Abstr. 13:1536.

Wilson, P.D., Kirby, M.A., and Parker, J.N., 1986. Comparisons of retinal ganglion cells projecting to ventral lateral geniculate nucleus and superior colliculus in the opossum. Soc. Neurosc. Abstr. 12:1038.

Ostrach, L., Kirby, M.A., and Chalupa, L.M., 1986. Topographic organization of retinocollicular projections in the fetal cat. Soc. Neurosc. Abstr. 12:119.

Kirby, M.A., and Chalupa, L.M., 1985. Retinal crowding reduces the size of dendritic fields of alpha ganglion cells. Soc. Neurosc. Abstr. 11:222.

Kirby, M.A., and Wilson, P.D., 1984. Axon count in the developing optic nerve of the North American opossum: Overproduction and elimination. Soc. Neurosc. Abstr. 10:467.

Wilson, P.D., and Kirby, M.A, 1984. X-, Y- and W-like cells in the lateral geniculate nucleus of the opossum. Soc. Neurosc. Abstr. 10:296.

Kirby, M.A., Clift-Forsberg, L., Wilson, P.D., and Rapsardi, S.L., 1981. The optic nerve of the North American opossum: An electron microscopic study. Soc. Neurosc. Abstr. 7:281.

Presentations

10/25/85 Presentation to the Society for Neuroscience, Dallas, TX. "Retinal crowding affects the size of the alpha ganglion cells in the cat's visual system."

11/10/86 Presentation to the Society for Neuroscience, Washington, D.C. "Topographic organization of the retinotectal projection in the fetal cat."

11/12/86 Presentation to the Society for Neuroscience, Washington, D.C. "Cell groups projecting to the superior colliculus and lateral geniculate nucleus ventralis of the opossum."

9/15/87 Presentation to the Society for Neuroscience, New Orleans, LA. "The decussation pattern of the developing retina of the fetal cat."

9/16/87 Presentation to the Society for Neuroscience, New Orleans, LA. "Functional reorganization of the feline visual system following prenatal damage."

5/3/88 Presentation to the Society for Research in Vision and Ophthalmology. Sarasota, FL "Do retinal projections account for cell death."

9/6/88 Presentation to the International Symposium on Retinal Generation and Regeneration, Banff, Canada. "Dendritic maturation of primate retinal ganglion cells."

11/11/88 Presentation to the Society for Neuroscience, Toronto, Canada. "Retinotopic order during development of the rat retinocollicular projection."

11/14/88 Presentation to the Society for Neuroscience, Toronto, Canada. "Morphological development of primate retinal ganglion cells."

5/5/89 Presentation at the Annual Meeting of the Association for Research in Vision and Ophthalmology, Sarasota, FL. "Early process outgrowth of primate ganglion cells."

6/29/89 Presentation at the Annual Meeting of the Association of Laboratory and Animal Science, Pomona, CA. "Animal Research: The need for informed response."

2/14/90 Presentation to International Conference on Neural Regulation and Transplantation. University of Singapore, Singapore. "Dendritic stratification of primate retinal ganglion cells during early outgrowth."

4/01/90 Presentation to the Association for Research in Vision and Ophthalmology, Sarasota, FL. "Centroperipheral patterns of dendritic stratification in primate retinal ganglion cells."

8/26/90 Presentation to the Joint Brazil Biomedical Societies, Casambau, Brazil. "Functional organization of the lateral geniculate nucleus in the North American opossum."

9/01/90 Presentation to the Department of Biophysics, Federal University of Rio de Janerio, Rio de Janerio. "Development of the mammalian retina."

8/6/91 Presentation to the International Brain Research Organization, Montreal, Canada. "Evidence for dendritic lengthening during formation of the fovea in the rhesus monkey."

4/29/91 Presentation to the Association for Research in Vision and Ophthalmology, Sarasota, FL. "Lateral migration of differentiated cells forms the primate fovea."

6/24/91 Presentation to the Departments of Ophthalmology and Structural Biology, University of Washington, Seattle, WA. "Mechanisms underlying prenatal development of retinal ganglion cells in the rhesus monkey."

8/5/91 Presentation to the International Brain Research Organization, Montreal, Canada. "Radial migration forms the foveal depression in the rhesus monkey."

5/12/92 Presentation to Fourth Graders at the Arroyo Verde School, San Bernardino, CA. "Biology of the body"

6/11/92 Presentation to the National Institute of Health, National Eye Institute, Washington, D.C. "Development of primate retina."

11/21/92 Presentation to the Society for Neuroscience, Anaheim, CA. "Prenatal development of horizontal cells in the retina of the rhesus monkey."

11/21/92 Presentation to the Society for Neuroscience, Anaheim, CA. "Photoreceptor topography in the retinae of anubis baboons." November, 1992.

11/23/92 Presentation to the Society for Neuroscience, Anaheim, CA. "Reorganization of retinocollicular topography following fetal enucleation in the cat." November, 1992.

11/1/93 Presentation to the Society for Neuroscience, Washington, D.C. "The role of bistratified cells in the establishment of retinal mosaics in the fetal rhesus macaque." November, 1993.

11/2/93 Presentation to the Society for Neuroscience, Washington, D.C. "Retinocollicular topography following monocular enucleation in the North American opossum." November, 1993.

11/2/93 Presentation to the Society for Neuroscience, Washington, D.C. "Measurement of foveal area in the rhesus monkey during fetal development." November, 1993.

11/3/93 Presentation to the Society for Neuroscience, Washington, D.C. "Short-term effects of proton microbeam irradiation on feline LGN." November, 1993.

11/15/94 Presentation to the Society for Neuroscience, Miami Beach, FL. "Gliogenesis in the retina of the macaque."

4/15/95 Presentation to the Society for Research in Vision and Ophthalmology, Ft. Lauderdale, Fl. "The development of glial cells in the retina of the rhesus monkey."

11/17/96 Presentation to the Society for Research in Vision and Ophthalmology, Ft. Lauderdale, Fl. "Development of the dendritic arbor of ganglion cells in the extreme inner and outer plexiform layer of the macaque retina."

4/18/97 Presentation to the Society for Research in Vision and Ophthalmology, Ft. Lauderdale, Fl. "The role of Brn 3.2 in retinal development."

10/28/99 Presentation to the Society for Neuroscience, Miami Beach, FL. "FGF-15 Influences retinal ganglion cell differentiation."

10/22/2001 Presentation to the Society for Neuroscience, San Diego California. Neural innervation of the mouse cervix.

Invited lectures

1/27/85 Presentation to the Departments of Biology and Psychology, University of California, Riverside. "Receptive field properties of cells in the opossum's lateral geniculate nucleus of the thalamus."

12/15/85 Presentation to the Graduate Group, Claremont Colleges. "Receptive field properties and latencies of cells in the lateral geniculate nucleus of a marsupial."

6/27/86 Presentation to the Department of Psychology, University of California Riverside. "Mechanisms establishing the visual system of the fetal cat."

8/8/86 Presentation to the Department of Anatomy, Loma Linda University. "Mechanisms of prenatal development of the cat's visual system."

7/15/87 Presentation to the Departments of Animal Physiology and Psychology, University of California, Davis. "Prenatal development of retinal ganglion cells in the primate visual system."

8/29/87 Presentation to the Redondo Beach Adventist Church. "Higher Education."

9/87 Presentation to the San Bernardino City Council. "Animal Research."

6/29/88 Presentation to the Department of Pediatrics, Huntington Memorial Hospital. "Neural plasticity. Is it better to have CNS damage prenatally or as an adult?"

7/7/88 Presentation to California State Polytechnic University, Pomona, CA, Symposium. "Prenatal development of the primate visual system."

3/30/89 Presentation to the Doheny Eye Institute, University of Southern California. "Mechanisms of early process outgrowth in the retina of the fetal monkey."

8/27/90 Keynote Presentation to the Joint Brazilian Societies of Experimental Biology, Casambu, Brazil. "Development of the primate retina."

10/09/91 Presentation to the American Cancer Society - Inland Chapter. "Use of animals in pediatric research."

12/22/91 Presentation to the Department of Gynecology and Obstetrics, Loma Linda University. "Development of the Brain."

4/06/92 Presentation to the Department of Pharmacology, Oxford University, Oxford, England. "Prenatal development of the primate fovea."

4/23/92 Presentation to the Department of Neurobiology, Max Planck Institute, Frankfurt, Germany. "Mechanisms underlying formation of the primate retina."

6/23/92 Presentation to the Saving Lives Coalition, Washington, D.C. "Animal Models in Pediatric Research."

6/22/92 Presentation to the National Institutes of Health-National Eye Institute. "Mechanisms of prenatal development of the primate fovea." August, 1992.

11/19/92 Presentation to the Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, CA. "Mechanisms of Fetal Development in the Primate Fovea."

10/31/93 Presentation to the Proton Therapy Conference Overview Group (PTCOG), Cambridge, MA. "Effects of proton irradiation in the cat's LGN." October, 1993.

12/19/94 Invited presentation to the Singapore Neuroscience Society, 2nd International meeting of Pacific Rim Nations of Neuroscience. "Mechanisms of foveal development in the rhesus monkey."

10/21/99 Presentation to the Howard Hughes Institute, University of California, San Diego. "The role of Brn 3.2 in retinal ganglion cell genesis".

8/19/99 Lecture to the Department of Biological Structure, University of Washington, Seattle, Seattle, Washington. "Brn3.2 and retinal development."

9/1/99 Presentation to the Department of Orthopedic Surgery, Karolinska Medical Center, Karolinska University, Stockholm, Sweden. "Genetic Control of Retinal Ganglion Cell Proliferation. Lessons for Bone Formation?"

11/25/99 Lecture to the Graduate Group in Speech Communication-Gross Organization of the Human Brain. University of Redlands, Redlands, CA.

8/14/2001 Invited presentation to the International Ophthalmology and Visual Neuroscience Meeting (INOVS). "A Tale of Two Genes: Brn 3.2 and FGF-15", Sydney, Australia.

1/18/2002 Invited lecture to the Dept. of Ophthalmology, LLU. The role of two gene classes in determining retinal development.

6/27/2002 Invited lecture for the 4th International Symposium of Ophthalmology (ISO) of China. "The role of FGF-15 and FGF receptors on the fate determination of retinal ganglion cells", Shantou, China

Committees

• Chair Loma Linda University Animal Research Committee (2001-Present)
• Member California Biomedical Society
• Member Graduate Retreat Planning Committee, Loma Linda University
• Co-chair School of Medicine MSTP Committee, Loma Linda University
• Member School of Medicine Summer Undergraduate Research Committee, Loma Linda University
• Member Transplant Research Study Group, Loma Linda University
• Member School of Medicine Task Force for Clinical Faculty Research (L. Longo-Chair)
• Member School of Medicine Promotions Committee (1996-2000)
• Member Animal Research Committee, LLU (1999-2000)
• Member Subcommittee on Graduate Education in the Basic Sciences and
• Basis Science Departments (2000-2001)
• Member Loma Linda University School of Medicine Academic Review Committee (2002-present)
• Member Loma Linda University School of Dentistry Academic Review Committee (2001-present)
• Chairman Research Governance Committee, Department of Pediatrics, Loma Linda University
• Assoc. Dir. Loma Linda Pediatric Brain Tumor Research Center, Loma Linda University Medical Center
• Co-chair. University (IFAC) Committee for the Development of Faculty Research (S. Knutson- Co-chair)
• Co-chair. Infant Neonatal Research Group (INRG) Committee, Department of Pediatrics, Loma Linda University
• Represen. Loma Linda University Children's Hospital to National Association of Children's Hospitals and Related Institutions, Inc. (NACHRI)
• Reviewer Journal of Visual Neuroscience
• Reviewer Journal of Neuroscience
• Reviewer Journal of Comparative Neurology (Ad Hoc)
• Reviewer Journal of Developmental Brain Research (Ad Hoc)
• Reviewer National Science Foundation (Ad Hoc)
  Reviewer National Institutes of Health (Special Session Reviewer)
• Reviewer Journal of Neurosurgery

Community committees

• Chairman Citizens for Concerned Research, San Bernardino
• Chairman Ministries Committee, Campus Hill Church
• Chairman Nominating Committee, Campus Hill Church
• Member Representative to South California Conference, Campus Hill Church
• Member Board Campus Hill Church
• Teacher Kindergarten Sabbath School, Campus Hill Church

Students trained

• Kevin Sawchuck - LLU medical School graduate, Post-grad. of the University of Chicago Medical School.
  
• J. Peter A. Yhip - LLU medical school graduate, currently practicing neuro-radiologist, University of Illinois
  
• Dawn DeJager - Medical Graduate, University of Iowa, School of Medicine
  Susan Meacham - Graduate Student (non-thesis Master's), Department of Anatomy, Loma Linda University
  
• Sophia Kim - Medical Student Graduate, School of Medicine, Loma Linda University
  
• Alan Richburg - Medical Student Graduate, Department of Anatomy, Loma Linda University - Master's Thesis - "Topographic development of the cortico-collicular projection in the neonatal rat." B Currently, practicing physician in sports medicine, U.C. San Diego.
  
• John Molitor - Medical Student Graduate, LLUMC, currently resident in family medicine, LLUMC.
  
• Daryl Lau - Graduate Student, Department of Anatomy
  
• Chad Reder - "Physiological and Morphological alternation in the feline LGN following Proton Irradiation." Master's Thesis, Department of Anatomy, Medical graduate LLU, currently ophthalmology resident The Johns Hopkins University.
  
• Quintin Fischer - "The role of binocular interaction in the development of the mammallian retinocollicular projection". Doctoral Dissertation-U.C. Riverside, currently postdoc U. of Kansas
  
• Thomas Steineke, "Development of Retinal Ganglion Cells in the Fetal Rhesus Monkey". Doctoral Dissertation. Medical Graduate, Johns Hopkins University, currently neurosurgery resident UCLA
  
• Kimberly Myruski - Graduate Student, "Evaluation of Nitric oxide in Respiratory Distress Syndrome." Master's Thesis. Currently medical student graduate from Thomas Jefferson,Medical School, Washington, D.C.
  
• Allen Jobe - Dental Student, LLU
  
• Michael Snyder - Graduate Student LLU, "Development of Putative Blue Retinal Ganglion Cells of the Rhesus Macaque". Master's Thesis LLU. Currently 4th year medical student LLU
  
• John Kline, Medical graduate LLU, currently resident in emergency medicine and surgery, LLUMC.
  
• Wilson De Melo, Jr., Graduate student Brazil
  
• Kristi Rao, Graduate Student LLU, Dissertation in progress.
  
• Oceguera, Luis, Graduate Student Student LLU, Master's Thesis in progress.
  
• Greg Allen, MSTP student
  
• Coleen Moran-LLU Graduate Student, Department of Anatomy.
  
• Ross Pender-La Serria Undergradute Student
  
• Kristi Rao-LLU Graduate Student, Department of Physiology
  
• Jevon Vanterpool-Graduate Student, Department of Physiology
  

Revised 12-02-02

[Top]