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May 10, 2001

Loma Linda University Cancer Institute


Cancer Surveillance Program releases new data

While men in Inyo, Mono, Riverside, and San Bernardino counties now face a declining risk of cancer, the risk to women in the four-county region has remained constant in recent years, according to a report of cancer incidence and mortality from 1988 to 1998 released by the Desert Sierra Cancer Surveillance Program (DSCSP) at a press conference on Wednesday, April 25.

Death from cervical cancer has risen among non-Hispanic white women while declining statewide—a troubling indicator given the screening tests available, according to researchers at Loma Linda University Cancer Institute, which operates the DSCSP.

Mr. Cheatham (right) introduces Dr. Morgan (left) and Dr. King who released new data on cancer incidence and mortality during a press conference held Wednesday, April 25.

According to Alan King, MD, medical director of the DSCSP, cervical cancer is completely preventable with proper screening.

Cervical cancer is often associated with the presence of human papilloma virus, a condition that can lead to cancer if not detected in time. But the virus is easily detected and treated even in medically underserved women with the many low-cost programs available.

“There should be no cases of cervical cancer,” said John Morgan, DrPH, cancer epidemiologist with the program. “These are deaths that should not be occurring.”

Drs. King and Morgan encouraged women to seek out low- or no-cost screening programs, such as the breast and cervical cancer early detection program, through their county health department.

“There are two screening tests that save lives. The most important is the Pap test. X-ray mammography is the second most important,” Dr. King said. “We know we can detect breast cancer earlier with mammography. The risk of dying from breast cancer is decreased by 60 percent if you get regular mammograms.”

According to the report, the continuation of the unacceptably high overall risk of cancer among women in the region, the state, and the nation is the consequence of a failure by women to reduce cigarette smoking since the 1970s. However, women in the Desert Sierra region did exhibit a steady decline in the risk of colorectal cancer.

According to the researchers, the decline in age-adjusted risk of cancer among men is consistent with similar declines measured statewide and nationally. They attribute the decline to reductions in tobacco use by men since the 1970s, early detection of premalignant intestinal polyps, and early detection of prostate cancer as the result of prostate-specific antigen testing.

From 1994 to 1998, Desert Sierra men and women had higher age-adjusted incidence and mortality rates for lung and bronchus cancer than the statewide average. The Desert Sierra population also had higher mortality rates for all cancers combined and for cancers originating in the colon and rectum, colon, and kidney and renal pelvis. These findings are consistent with the slightly higher prevalence of tobacco smoking measured in Riverside and San Bernardino counties when compared to the statewide average and with delayed diagnosis of screen-detectable cancers in the region when compared to the state. Lung and bronchus cancer accounted for 1,409 of the 4,916 cancer deaths among DSCSP residents in 1998.

The report also found that both men and women in the Desert Sierra region had a lower incidence for some cancers compared with the rest of the state, including cancers that start in the liver and stomach. They also had a lower risk for Kaposi’s sarcoma and non-Hodgkin’s lymphoma, which is consistent with the lower prevalence of HIV/AIDS reported in this region when compared to the Bay Area and Los Angeles County.

The annual report is the program’s sixth on cancer incidence and the third on cancer mortality released for the four counties. It uses data for new cancer cases added into the DSCSP active database prior to September 14, 2000, and deaths from cancer among residents of the region from 1988 to 1998.

The desert sierra cancer surveillance program (DSCSP) is one of 10 regional population-based cancer registries that, since 1988, form the California Cancer Registry (CCR).

The DSCSP serves as Region 5 of the CCR, California’s legally mandated cancer reporting system. As one of the largest population-based cancer registries in the world, the CCR provides cancer surveillance for the 33 million residents of California.

This state-of-the-art cancer surveillance system provides measurement of cancer incidence in California with details regarding age, gender, and race/ethnicity; assessment of regional cancer rates, trends, and concerns in each of 10 regions of California; and a rich, confidential database that supports research into the causes of cancer and identification of methods that maximize utilization of cancer control and prevention.

Since 1988, Loma Linda University Cancer Institute, part of Loma Linda University Medical Center, has received funding from the California Department of Health Services for operation of the DSCSP, which serves approximately one-tenth of the California population.

Late in 1995, the Centers for Disease Control and Prevention awarded additional funds for expansion of the research component of the DSCSP and for development of an annual scientific report of cancer incidence in the region. In 1999, assessment of cancer mortality within the DSCSP was added to the annual report.

At the press conference, researchers announced that the California Cancer Registry, and with it the DSCSP, has been designated a new member of the National Cancer Institute’s surveillance, epidemiology, and end results (SEER) program. The SEER program collects cancer data on a routine basis from designated population-based cancer registries in various areas of the United States. The data used in this system provides trends in cancer incidence, mortality, and patient survival, and represents the most important source for formulating national cancer control policy and new epidemiologic research in the United States.

For more information on cancer surveillance, prevention, screening, early diagnosis, or treatment, call the cancer information and referral service at (800) 78-CANCER (782-2623). This is a community service provided by Loma Linda University Cancer Institute.

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