Barbara Holshouser, PhD Professor, Radiation Technology School of Allied Health Professions Professor, Radiology School of Medicine Professor, Basic Sciences School of Medicine

Research & Grantsmanship 

  Funded Research Project (PI)

• Predicting Adult TBI Patient Outcomes with 1H-MRS ( 11/2002 - 1/2008 )

• Proton MR Spectroscopy to Monitor Brain Metabolite Changes after Plasma Detoxification Treatment of Hepatic Encephalopathy in Subjects with Decompensated Cirrhosis ( 2/2004 - 12/2004 )

  Funded Research Project (CI)

• Pediatric TBI and DAI: Normal Appearing Brain is not Normal ( 6/2007 - 6/2011 )

• Brain Activity and the perception of faces.  PI: Dr. Paul Zak ( 1/2009 - 1/2010 )

• Brain Activity and the perception of faces.  PI:  Dr. Paul Zak. ( 6/2008 - 6/2009 )

• Functional Brain Activation, neuromodulators and social cognition ( 1/2004 - Present )

• Predicting Outcome in prostate cancer patients; comparison of traditional MR imaging techniques with high resolution endorectal MR imaging and spectroscopy ( 1/2003 - Present )

• MR Spectroscopy for Prostate Cancer Localization ( 1/2003 - Present )

• The Role of Magnetic Resonance Imaging and Spectroscopy in Evaluation of Timing and Etiology of Early Brain Injury in Neonates ( 1/2003 - Present )

• Iron Metabolism Alterations in Alzheimer's Disease ( 1/2003 - Present )

• Predicting Outcome in Children Suffering Non-accidental Trauma: Comparison of Traditional MR Imaging Techniques with a New High-resolution, Blood Sensitive MR Technique and Magnetic Resonance Spectroscopy ( 1/2002 - Present )

• The role of magnetic resonance techniques in the assessment and prognosis of acquired neurological disorders ( 1/2002 - Present )

• Comparision of a new high-resolution blood-sensitive magnetic resonance imaging technique with magnetic resonance spectroscopy in predicting outcome in adults experiencing severe traumatic brain injury ( 1/2002 - Present )

• Proton Magnetic Resonance Spectroscopy in Children with Acute Central Nervous System Injury ( 1/1995 - Present )

  Non-Funded Research Project

• Identifying MR Imaging and Spectroscopic Markers of Brain Inury after non-accidental trauma. ( 5/2008 - 5/2010 )

• Multinuclear MR spectroscopy: Testing new coils for acquiring phosphorous and carbon spectroscopy. ( 1/2009 - 1/2010 )

  Abstracts Reporting Research -- Peer Reviewed

• Ashwal S, Holshouser B, Tong K. "Proton magnetic resonance spectroscopy imaging detects diffuse axonal injury in pediatric traumatic brain injury ." European Journal of Pediatric Neurology 9. (2005): 137-. ( 7/2005 )

• Thomas AK;Jacobson JP;Holshouser B;Bailey LL;Kido DK. "Occult Brain Microhemorrhages Associated with Cardiopulmunary Bypass in Some Infants and Children." ASNR . (2005): -. ( 1/2005 )

• Holshouser B;Babikian T;Freier MC;Tong K;Burley T;Riggs ML. "Proton spectroscopy predicts neuropsychological outcome after pediatric traumatic brain injury." Proc Intl Soc Mag Reson Med . (2005): 1232-1232. ( 1/2005 )

• Tong KA;Ashwal S;Shutter L;Wall C;Nickerson J;Aguilera A;Holshouser BA. "Clinical Correlation of Hemorrhagic Shearing Lesions in Children and Adults with Traumatic Brain Injury." J Neurotrauma 21. (2004): 1275-1275. ( 8/2004 )

• Holshouser BA, Lee A, Tong KA, Kedlaya D, Shutter LA. "Proton MRS predicts disability and employability in severely injured TBI patients." J Neurotrauma 21. (2004): 1294-. ( 8/2004 )