Loma Linda University

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Faculty Directory
  
Daila Gridley, PhD
Professor, Basic Sciences
School of Medicine
Professor, Radiation Medicine
School of Medicine
Member, Microbiology&Molecular Gen, SM, Faculty of Graduate Studies
Research & Grantsmanship    Funded Research Project (PI)
  • Co-PI on study funded by Department of Defense (DOD): Radiation Medicine Central Nervous System Studies (PI: JM Slater). External funding: yes, 2010-2012 ( 7/2010 - 6/2011 )
     
  • PI on study funded by Department of Energy (DOE): Th Cell Gene Expression and Function in Response to Low Dose and Acute Radiation. External funding: yes, 2007 – 2011 ( 7/2010 - 6/2011 )
    Co-Investigators: MJ Pecaut, X Luo-Owen, A Rizvi*
  • PI on study funded by The Randolph Hearst Foundation: Establishing a Biological Marker for Cancer Patients Who Are Hypersensitive to Radiation. External funding: yes, 2005 – 2012 ( 7/2010 - 6/2011 )
    Co-Investigators: JM Slater, JD Slater, DA Bush
  • PI on Task funded by NASA: Radiation, immune System and Tumor Growth (Cooperative Research in Proton Space Radiation; overall PI: JM Slater). External funding: yes, 2009 – 2011. ( 7/2010 - 6/2011 )
    Co-Investigators: MJ Pecaut, J Tian, A Rizvi*
  • Co-PI on portion of study funded by Department of Defense (DOD): Study To Measure Biologic Effects Modulated by Scanning Techniques Using Proton Beam (Overall PI: JM Slater). External Funding: yes, 2007-2011 ( 7/2010 - 6/2011 )
    Co-Investigators: X Luo-Owen, Tanya L. Freeman*
  • PI of study funded by Department of Energy (DOE): Th Cell Gene Expression and Function in Response to Low Dose and Acute Radiation. External funding: yes, 2007 – 2011 Co-Investigators: MJ Pecaut, X Luo-Owen, A Rizvi* ( 7/2009 - 6/2010 )
  • PI of study partially funded by NASA: Radiation, immune System and Tumor Growth (Co-PI: JM Slater). External funding: yes, 2009 – 2011. Co-Investigators: MJ Pecaut, J Tian, A Rizvi* ( 7/2009 - 6/2010 )
  • PI of study funded by Department of Defense (DOD): Study To Measure Biologic Effects Modulated by Scanning Techniques Using Proton Beam (Co-PI: JM Slater).. External Funding: yes, 2007-2011. Co-Investigator: X Luo-Owen ( 7/2009 - 6/2010 )
  • PI of study funded by The Randolph Hearst Foundation: Establishing a Biological Marker for Cancer Patients Who Are Hypersensitive to Radiation. External funding: yes, 2005 – 2011. Co-Investigators: JM Slater, JD Slater, DA Bush ( 6/2009 - 6/2010 )
  • PI of study funded by Department of Energy (DOE): Mechanisms of Low Dose Radiation-induced T Helper Cell Function. External funding: yes, 2005 – 2008. Co-Investigators: MJ Pecaut, A. Rizvi* CSP Room A-1010 ( 7/2008 - 6/2009 )
  • PI of study funded by Department of Energy (DOE): Th Cell Gene Expression and Function in Response to Low Dose and Acute Radiation. External funding: yes, 2007 – 2010. Co-Investigators: MJ Pecaut, X Luo-Owen, A Rizvi* CSP Room A-1010 ( 7/2008 - 6/2009 )
  • PI of study funded by The Randolph Hearst Foundation: Establishing a Biological Marker for Cancer Patients Who Are Hypersensitive to Radiation. External funding: yes, 2005 – 2010 Co-Investigators: JM Slater, JD Slater, DA Bush, X Luo-Owen CSP Room A-1010 ( 7/2008 - 6/2009 )
  • PI of study partially funded by NASA: Immune Modulation of Acute Radiation Effects (Photons, Protons, and Simulated Solar Flare Protons) by Low-dose/Low-dose-rate Radiation. External funding: yes, 2007 – 2008. Co-Investigators: MJ Pecaut, X Luo-Owen, J Tian, G Coutrakon, JM Slater, A Rizvi* CSP Room A-1010 ( 7/2008 - 6/2009 )
  • PI of study partially funded by NASA: Evaluation of Metalloporphyrin Radioprotectants in Rodent Models With Tumor. External funding: yes, 2007 – 2008. Co-Investigators: MJ Pecaut, JD Crapo, JM Slater, AY Makinde* CSP Room A-1010 ( 7/2008 - 6/2009 )
  • Co-PI of study funded by Department of Defense (DOD): Study To Measure Biologic Effects Modulated by Scanning Techniques Using Proton Beam. External Funding: yes, 2007-2010. Co-Investigators: JM Slater (Co-PI), X Luo-Owen CSP Room A-1010 ( 7/2008 - 6/2009 )
  • PI of study funded by Department of Energy (DOE): Mechanisms of Low Dose Radiation-induced T Helper Cell Function. External funding: yes, 2005 – 2008. ( 7/2007 - 6/2008 )
    Co-Investigators: MJ Pecaut, A. Rizvi*
  •  PI of study funded by Department of Energy (DOE): Th Cell Gene Expression and Function in Response to Low Dose and Acute Radiation. External funding: yes, 2007 – 2010. ( 7/2007 - 6/2008 )
    Co-Investigators: MJ Pecaut, X Luo-Owen, A Rizvi*
  •  PI of study funded by The Randolph Hearst Foundation: Establishing a Biological Marker for Cancer Patients Who Are Hypersensitive to Radiation. External funding: yes, 2005 – 2009 ( 7/2007 - 6/2008 )
    Co-Investigators: JM Slater, JD Slater, DA Bush, X Luo-Owen
  • PI of study partially funded by NASA: Immune Modulation of Acute Radiation Effects (Photons, Protons, and Simulated Solar Flare Protons) by Low-dose/Low-dose-rate Radiation. External funding: yes, 2007 – 2008.  ( 7/2007 - 6/2008 )
    Co-Investigators: MJ Pecaut, X Luo-Owen, J Tian, G Coutrakon, JM Slater, A Rizvi*
  • PI of study partially funded by NASA: Evaluation of Metalloporphyrin Radioprotectants in Rodent Models With Tumor. External funding: yes, 2007 – 2008. ( 7/2007 - 6/2008 )
    Co-Investigators: MJ Pecaut, X Luo-Owen, J Tian, G Coutrakon, JM Slater, A Rizvi*
  • PI of study partially funded by NASA: Evaluation of Metalloporphyrin Radioprotectants in Rodent Models With Tumor. External funding: yes, 2007 – 2008. ( 7/2007 - 6/2008 )
    Co-Investigators: MJ Pecaut, JD Crapo, JM Slater, AY Makinde*
  • Co-PI of study funded by Department of defense (DOD): Study To Measure Biologic Effects Modulated by Scanning Techniques Using Proton Beam. External Funding: yes, 2007-2010.  ( 7/2007 - 6/2008 )
    Co-Investigators: JM Slater (Co-PI), X Luo-Owen
  • PI of study funded by Department of Energy (DOE): Mechanisms of Low Dose Radiation-induced T Helper Cell Function. External funding: yes, 2005 – 2008. ( 7/2007 - 6/2008 )
    Co-Investigators: MJ Pecaut, A. Rizvi* 
  • PI of study funded by Department of Energy (DOE): Mechanisms of Low Dose Radiation-induced T Helper Cell Function. External funding: yes, 2005 – 2008. ( 7/2007 - 6/2008 )
    Co-Investigators: MJ Pecaut, A. Rizvi*
  • Study Funded by Dept. of Energy (DOE) ( 7/2006 - 6/2007 )
  • Study Funded by Dept. of Energy (DOE) ( 7/2006 - 6/2007 )
  • Study Funded by The Randolph Hearst Foundation ( 7/2006 - 6/2007 )
  • Study - Simulated Solar Flare Protons ( 7/2006 - 6/2007 )
  • Study - Radioprotectants ( 7/2006 - 6/2007 )
  • Study - Proton Beam Characterization ( 7/2006 - 6/2007 )
  • Study - Proton Beam Characterization ( 7/2005 - 6/2006 )
  • Study - Simulated Solar Flare Protons ( 7/2005 - 6/2006 )
  • Study - Radioprotectants ( 7/2005 - 6/2006 )
  • Study Funded by Dept. of Energy (DOE) ( 7/2005 - 6/2006 )
  • Study Funded by The Randolph Hearst Foundation ( 7/2005 - 6/2006 )
  • Senior author or co-author of 5 poster presentations at Annual Postgraduate Convention (APC), ( 7/2004 - 6/2005 )
  • Modulation of immunity and tumor response to acute high dose radiation (gamma-rays, protons, and simulated solar flare protons) by low-dose/low-dose rate radiation priming. ( 7/2004 - 6/2005 )
  • Evaluation of AEOL 10113 as a radioprotectant against whole-body irradiation. ( 7/2004 - 6/2005 )
  • Molecular and biological changes induced by proton and photon irradiated normal human small airway epithelial cells (SAECs). ( 7/2004 - 6/2005 )
  • Senior author or co-author of 7 poster presentations at Seventh Annual Research Symposium, ( 7/2004 - 6/2005 )
  • Principal Investigator on an RO1 grant submitted to NIH/NIAID ( 7/2004 - 6/2005 )
  • OTHER ( 7/2004 - 6/2005 )
  Funded Research Project (CI)
  • Co-I on grant funded by Department of Energy (DOE): Low Dose Ionizing Radiation Modulates Immune Function (PI: GA Nelson). External Funding: yes, 2008-2011 ( 7/2010 - 6/2011 )
     
  • Co-Investigator in study: Mechanisms of Psychosocial Influences on Prostate Cancer. Principal Investigator: DL Bellinger ( 6/2009 - 7/2010 )
  • Collaborator on study: Development and Characterization of a Novel Strategy to Enhance Delivery of Stem Cells to Improve Healing in Traumatic Musculoskeletal Injuries. Hypothesis Development Award. Principal Investigator: Sue Hall, MD, PhD (Loma Linda VA) ( 7/2009 - 6/2010 )
  • Co-Investigator in Study: Low Dose Ionizing Radiation Modulates Immune Function. Principal Investigator GA Nelson ( 6/2009 - 6/2010 )
  • Co-Investigator in study: CNS and Immune System Communication After Proton Radiation: Phagocytic Cell Function. Principal Investigator: MJ Pecaut ( 6/2009 - 6/2010 )
  • Co-Investigator: CNS, Phagocytic Cells and Proton Radiation CNS and Immune System Communication After Proton Radiation: Phagocytic Cell Function. Principal Investigator: MJ Pecaut ( 7/2008 - 6/2009 )
  • Co-Investigator: Mechanisms of Psychosocial Influences on Prostate Cancer. Principal Investigator: DL Bellinger ( 7/2008 - 6/2009 )
  • CNS and Immune System Communication After Proton Radiation: Phagocytic Cell Function. Principal Investigator: MJ Pecaut  ( 7/2007 - 6/2008 )
     
  • Space Radiation Effects on Structure and Function of Bone. Principal Investigator: TA Bateman (Clemson University) ( 7/2007 - 6/2008 )
     
  • Study - Head-only Proton Irradiation ( 7/2006 - 6/2007 )
  • Study - Space Radiation and Bone ( 7/2006 - 6/2007 )
  • Study - Head-only Proton Irradiation ( 7/2005 - 6/2006 )
  • Study - Immune System and Aging ( 7/2005 - 6/2006 )
  • Study - Space Radiation and Bone ( 7/2005 - 6/2006 )
  Non-Funded Research Project
  • Collaborator on study funded by Congressionally Directed Medical Research Programs (CDMRP, Army): Development and Characterization of a Novel Strategy to Enhance Delivery of Stem Cells to Improve Healing in Traumatic Musculoskeletal Injuries. (PI: S. Hall, Loma Linda VA).  2010-2011 ( 7/2010 - 6/2011 )
     
  • Collaborator on Loma Linda VA Program Project: Mechanisms for Regeneration of Endosteal Bone (PI: S. Hall, Loma Linda VA). 2011-2014 ( 7/2010 - 6/2011 )
     
  Grant Proposals--Submitted
  • PI on study submitted to St. Baldrick’s Foundation: Infrastructure - Cytokine Profiling (for equipment). External funding: PENDING, 2011-2012. Co-Investigators: MJ Pecaut, XW Mao  ( 7/2010 - 6/2011 )
     
  • Co-I on grant submitted to NASA: Impact of Spaceflight on Astronaut Antibody Responses; NRA Research and Technology Development to Support Crew Health and Performance in Space Exploration Missions (PI: MJ Pecaut). Review is PENDING 2011-2014. ( 7/2010 - 6/2011 )
     
  • Co-I on grant submitted to NASA: Role of NADPH Oxidase in Radiation-induced Remodeling of Neurovascular Unit in Mouse Hippocampus; NNJ11ZSA001N: Ground-Based Studies in Space Radiobiology (PI: XW Mao). Review is PENDING, 2012-2014.  ( 7/2010 - 6/2011 )
     
  Abstracts Reporting Research -- Peer Reviewed
  • Pecaut, M.J., Bayeta, E., Luo-Owen, X., Perez, C., Rightnar, S., Harding, G., Gifford, P., and Gridley, D.S. The impact of whole body proton radiation on immune-CNS communication. Presented at 18th Annual Psychoneuroimmunology Research Society (PNIRS) Meeting. Chicago, IL. Poster #25. June 8-11, 2011. ( 7/2010 - 6/2011 )
     
  • Dulcich, M.S., Hartman, R.E., Gifford, P., Molinaro, C., Luo-Owen, X., Kroh, J. Gridley, D.S., and Bellinger, D.L. Aging and stress effects on behavioral outcomes and tumor growth in a mouse model of prostate cancer. Presented at 18th Annual Psychoneuroimmunology Research Society (PNIRS) Meeting. Chicago, IL. Poster #71. June 8-11, 2011. ( 7/2010 - 6/2011 )
     
  • Mao, X.W., Mekonnen, T., and Gridley, D.S. Detection of early-stage apoptosis in mouse brain after low-dose of gamma irradiation. Presented at International Symposium for Radiation Research and Medical Physics (Heavy Ion Symposium Japan Satellite Meeting), Shanghai, China.
May 30-June 2, 2011. ( 7/2010 - 6/2011 )
     
  • King, G.L., Maks, C., Gridley, D.S., Kennedy, A.R., and Miller, A. Acute response to space radiation: prodromal syndrome in ferrets. Presented at 18th Humans in Space Symposium (sponsor: International Academy of Astronautics). Poster Session: Transit and Surface Poster B: Space Radiation. Abstract ID number 2249. Houston, TX. April 11-15, 2011. ( 7/2010 - 6/2011 )
     
  • Ravichandran, P., Periakaruppan, A., Ramesh, V., Hall, J.C., Zhang, Y., Jejelowo, O., Gridley, D.S., Wu, H., and Ramesh, G.T. Protons induce oxidative stress and alter antioxidant levels in epithelial cells. Presented at 18th Humans in Space Symposium (sponsor: International Academy of Astronautics). Abstract ID number 2321. Houston, TX. April 11-15, 2011. ( 7/2010 - 6/2011 )
     
  • Pecaut, M.J., Bayeta, E., and Gridley, D.S. Impact of the spaceflight environment on the immune system. Presented at Keystone Symposia’s meeting on Metabolic Responses to Extreme Conditions (Session on Space: Responses to Space Flight and Microgravity Simulation. Abstract Book, p. 50. Big Sky, Montana. April 1-5, 2011. ( 7/2010 - 6/2011 )
     
  • Hall, S.L., Chen, S.T., Mohan, S., Wergedal, J.E., Srivastava, A.K., Gridley, D.S., and Lau, K.H.W. Stem cell antigen 1 (Sca-1+) hematopoietic cell-based gene therapy with a modified fibroblast growth factor 2 (FGF2) produces contrasting skeletal effects on femur as opposed to tail vertebra in mice. Presented at Annual American Society of Bone and Mineral Research (ASBMR) meeting. Toronto, ON, CANADA. Oct 15-19, 2010. (oral presentation by Dr. Hall) ( 7/2010 - 6/2011 )
     
  • Gridley, D.S., Pecaut, M.J., Bayeta, E.J.M., Tian, J., Wroe, A.J., Rightnar, S., Kennedy, A.R., and Slater, J.M. Comparison of liver response after proton versus electron irradiation in a mouse model. Presented at 56th Annual Meeting of the Radiation Research Society (RRS). Poster PS2.62, Abstract Book p. 93. Maui, HI. Sept. 25-29, 2010. ( 7/2010 - 6/2011 )
     
  • Gridley, D.S., and Pecaut, M.J. Response of lymphocyte populations in different strain mice irradiated with iron ions. Presented at 56th Annual Meeting of the Radiation Research Society (RRS). Poster PS6.24, Abstract Book p. 159. Maui, HI. Sept. 25-29, 2010. ( 7/2010 - 6/2011 )
     
  • Rizvi, A., Luo-Owen, X., and Gridley, D.S. Cytokine profiles induced by exposure to low-dose radiation and simulated solar particle event protons. Presented at 56th Annual Meeting of the Radiation Research Society (RRS). Poster PS6.31, Abstract Book p. 161. Maui, HI. Sept. 25-29, 2010. ( 7/2010 - 6/2011 )
     
  • Pecaut, M.J., Bayeta, E.J.M., Pan, C., Perez, C.P., and Gridley. D.S. Does ethyl pyruvate act as a radioprotectant in macrophage cell lines? Presented at 56th Annual Meeting of the Radiation Research Society (RRS). Poster PS1.43, Abstract Book p. 65. Maui, HI. Sept. 25-29, 2010. ( 7/2010 - 6/2011 )
     
  • Mao, X.W., Mekonnen, T., Kennedy, A.R., and Gridley, D.S. Gene expression analysis of oxidative stress-initiated extracellular matrix remodeling in low-dose/low-dose-rate photon irradiated skin. Presented at 56th Annual Meeting of the Radiation Research Society (RRS). Poster PS5.21, Abstract Book p. 140. Maui, HI. Sept. 25-29, 2010. ( 7/2010 - 6/2011 )
     
  • Tian, J., Tian, S., Slater, J.M., and Gridley, D.S. Comparison of acute photon and proton effects on lung profibrosis and tissue remodeling-related genes and protein expressions with low-dose photon pre-irradiation. Presented at 56th Annual Meeting of the Radiation Research Society (RRS). Poster PS4.68, Abstract book p. 131. Maui, HI. Sept. 25-29, 2010. ( 7/2010 - 6/2011 )
     
  • Luo-Owen, X., Freeman, T.L., Perez, C., Crapo, J.D., Pecaut, M.J., Slater, J.M., and Gridley, D.S. The impact of a metalloporphyrin antioxidant on radiation response in two tumorigenically distinct lung cell types. Presented at 56th Annual Meeting of the Radiation Research Society (RRS). Poster PS1.27, Abstract Book p. 60. Maui, HI. Sept. 25-29, 2010. ( 7/2010 - 6/2011 )
     
  • Maks, C.J., Ware, J.H., Romero-Weaver, A., Sanzari, J.K., Wilson, J.M., Rightnar, S., Wroe, A.J., Gridley, D.S., Slater, J.M., and Kennedy, A.R. Investigation of proton and gamma irradiation on white blood cell counts in mice. Presented at 56th Annual Meeting of the Radiation Research Society (RRS). Poster PS6.36, Abstract Book p. 163. Maui, HI. Sept. 25-29, 2010. ( 7/2010 - 6/2011 )
     
  • Purgason, A., Zhang, Y., Govindarajan, R., Jejelowo, O., Gridley, D.S., Hamilton, S., and Wu, H. Molecular and histopathological changes in mouse intestinal tissue after proton exposure. Presented at 56th Annual Meeting of the Radiation Research Society (RRS). Poster PS4.51, Abstract Book p. 126. Maui, HI. Sept. 25-29, 2010.  ( 7/2010 - 6/2011 )
     
  • Baluchamy, S., Zhang, Y., Ramesh, V., Ravichandran, P., Hall, J.C., Jejelowo, O., Gridley, D., Wu, H., Ramesh, G.T. Oxidative stress mediated DNA damage and cell death in proton exposed mouse brain. Presented at 56th Annual Meeting of the Radiation Research Society (RRS). Poster PS4.67, Abstract Book p. 131. Maui, HI. Sept. 25-29, 2010. ( 7/2010 - 6/2011 )
     
  • Gridley DS, Pecaut MJ, Rizvi A, Coutrakon GB, Luo-Owen X, Makinde AY, Slater JM. Low-dose, low-dose-rate proton radiation modulates CD4+ T cell gene expression. Presented at the U.S. Department of Energy (DOE) Low Dose Radiation Research Investigators’ Workshop VIII. Bethesda, MD. Abstract Book, pp. 73-74. April 6-8, 2009. ( 4/2009 )
  • Tian J, Pecaut MJ, Coutrakon GB, Slater JM, Gridley DS. Response of extracellular matrix regulators in mouse lung after exposure to photons, protons and simulated solar particle event protons. Presented at the U.S. Department of Energy (DOE) Low Dose Radiation Research Investigators’ Workshop VIII. Bethesda, MD. Abstract Book, pp. 75-76. April 6-8, 2009. ( 4/2009 )
  • Gridley DS, Rizvi A, Luo-Owen X, Makinde, AY, Pecaut MJ. Low-dose, low-dose-rate photon radiation modifies leukocyte distribution and gene expression in CD4+ T cells. Presented at the U.S. Department of Energy (DOE) Low Dose Radiation Research Investigators’ Workshop VIII. Bethesda, MD. Abstract Book, pp. 71-72. April 6-8, 2009. ( 4/2009 )
  • Luo-Owen X, Rizvi A, Makinde AY, Coutrakon GB, Koss P, Pecaut MJ, Slater JM, Gridley DS. Effects of simulated solar particle event protons and low dose photons on Foxp3+ T regulatory cells. Presented at 99th Annual Meeting of the American Association for Cancer Research (AACR), San Diego, CA. Program Book p. 391. April 12-16, 2008. ( 4/2008 - 4/2009 )
  • Gridley DS, Pecaut MJ, Green LM, Nelson GA, Bianski B, Jones TA, Han HQ, Lacey D, Stodieck LS, Ferguson VL, Slater JM. Gene expression in thymus and liver of mice after spaceflight. Presented at 54th Annual Meeting of the Radiation Research Society (RRS) held in conjunction with meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO). Boston, MA. Abstract Book p. 117 (poster PS3641). Sept. 21-24, 2008. ( 9/2008 )
  • Makinde AY, Luo-Owen X, Slater JM, Crapo JD, Pearlstein RD, Gridley DS. Response of prostate cancer cell lines treated with radiation and MnTE-2-PyP. Presented at 54th Annual Meeting of the Radiation Research Society (RRS) held in conjunction with meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO). Boston, MA. Abstract Book p. 95 (poster PS3565). Sept. 21-24, 2008. ( 9/2008 )
  • Rizvi A, Pecaut MJ, Andres MJ, Coutrakon GB, Luo-Owen X, Slater JM, Gridley DS. Low dose/low dose rate radiation normalizes pro-survival proteins in CD4+ T cells from mice exposed to solar particle event. Presented at 54th Annual Meeting of the Radiation Research Society (RRS) held in conjunction with meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO). Boston, MA. Abstract Book p. 115 (poster PS3636). Sept. 21-24, 2008. ( 9/2008 )
  • Zhang Y, Clement J, Gridley DS, Rodhe L, Wu H. Comparison of protein expression profile changes in human fibroblasts induced by low doses of gamma rays and energetic protons. Presented at 37th COSPAR (Committee on Space Research) Scientific Assembly Meeting. Montreal, Canada. Program Book p. 240 (poster F46-0012-08), July 13-20, 2008. ( 7/2008 )
  • Zhang Y, Clement J, Gridley DS, Rodhe L, Wu H.  Comparison of protein expression profile changes in human fibroblasts induced by low doses of gamma rays and energetic protons. Presented at 19th Annual Space Radiation Investigator’s Workshop. Philadelphia, PA. Program p. 44 (poster CG141), June 30 – July 2, 2008. ( 6/2008 - 7/2008 )
  • Mao XW, Mekonnen T, Jones TA, Bianski B, Han HQ, Lacey D, Stodieck L, Ferguson V, Green LM, Nelson GA, Pecaut MJ, Gridley DS, Slater JM. Early effects of space flight condition on apoptosis in normal ocular and skin tissue. Presented at 19th Annual Space Radiation Investigator’s Workshop. Philadelphia, PA. Program p. 127 (Poster NC14), June 30 – July 2, 2008. ( 6/2008 - 7/2008 )
  • Baqai FP, Gridley DS, Bayeta E, Andres M, Luo-Owen X, Jones TA, Bianski B, Rizvi A, Stodieck L, Ferguson V, Green L, Nelson G, Pecaut MJ. Effects of spaceflight stress on anti-inflammatory response. Presented at 15th Annual Meeting of the Psychoneuroimmunology Society (PNIRS). Madison, WI. Abstract Book p. 28. May 28-31, 2008.   ( 7/2007 - 6/2008 )
     
  • Hada M, Lacy S, Gridley DS, Rusek A, Cucinotta FA, Wu H. Distribution of micronuclei in human fibroblasts across the Bragg curve of light and heavy ions. Presented at 13th International Congress of Radiation Research (ICRR) held in conjunction with the meeting of the Radiation Research Society (RRS). San Francisco, CA.  Abstract Book p. 166, July 7-12, 2007.  ( 7/2007 - 6/2008 )
     
  • Bandstra ER, Pecaut MJ, Anderson ER, Willey JS, De Carlo F, Stock SR, Gridley DS, Nelson GA, Bateman TA. Bone loss following proton irradiation. Presented at 23nd Annual Meeting of the American Society for Gravitational and Space Biology (ASGSB), NASA Research Park, Ames Research Center, Moffett Field, CA. October 25-28, 2007. Gravitational and Space Biology 21(1):16, 2007.   ( 7/2007 - 6/2008 )
     
  • Gridley DS, Rizvi A, Luo-Owen X, Makinde AY, Andres ML, Coutrakon GB, Koss P, Slater JM, Pecaut MJ. Low dose proton radiation-induced gene expression patterns in CD4+ T helper cells. Presented at DOE Low Dose Radiation Research Investigators’ Workshop VII. Washington, DC. Abstract Book page 83. January 21-23, 2008.  ( 7/2007 - 6/2008 )
     
  • Makinde AY, Rizvi A, Luo-Owen X, Crapo JD, Pearlstein RD, Slater JM, Gridley DS. Altered cytokine expression after treatment with MnTE-2-PyP and radiation in a prostate cancer model. Presented at 99th Annual Meeting of the American Association for Cancer Research (AACR), San Diego, CA. Program Book p. 162. April 12-16, 2008.  ( 7/2007 - 6/2008 )
     
  • Luo-Owen X, Rizvi A, Makinde AY, Coutrakon GB, Koss P, Pecaut MJ, Slater JM, Gridley DS. Effects of simulated solar particle event protons and low dose photons on Foxp3+ T regulatory cells. Presented at 99th Annual Meeting of the American Association for Cancer Research (AACR), San Diego, CA. Program Book p. 391. April 12-16, 2008.  ( 6/2007 - 6/2008 )
     
  • Baqai FP, Gridley DS, Bayeta E, Andres M, Luo-Owen X, Jones TA, Bianski B, Rizvi A, Stodieck L, Ferguson V, Green L, Nelson G, Pecaut MJ. Effects of spaceflight stress on anti-inflammatory response. Presented at 15th Annual Meeting of the Psychoneuroimmunology Society (PNIRS). Madison, WI. Abstract Book p. 28. May 28-31, 2008. ( 5/2008 )
  • Gridley D.S. Oral presentation during Radio-oxidative Stress and Inflammation Break-out Session. Topic: Low dose proton radiation-induced gene expression patterns in CD4+ T helper cells. Session Coordinator: Douglas Spitz, PhD. Presented at Department of Energy (DOE) Low Dose Radiation Research Investigators’ Workshop VII. Washington, DC, January 21-23, 2008. ( 7/2007 - 5/2008 )
     
  •  Gridley DS, Rizvi A, Makinde AY, Luo X, Tian J, Andres M, Coutrakon GB, Pecaut MJ. Low-dose rate photons and simulated solar particle event protons: gene expression in liver. Presented at 13th International Congress of Radiation Research (ICRR) hosted by the Radiation Research Society (RRS). San Francisco, CA. Abstract Book p. 244, July 7-12, 2007.  ( 7/2007 - 5/2008 )
     
  • Makinde AY, Rizvi A, Luo-Owen X, Crapo JD, Pearlstein RD, Slater JM, Gridley DS. Altered cytokine expression after treatment with MnTE-2-PyP and radiation in a prostate cancer model. Presented at 99th Annual Meeting of the American Association for Cancer Research (AACR), San Diego, CA. Program Book p. 162. April 12-16, 2008. ( 4/2008 )
  • Gridley DS, Rizvi A, Luo-Owen X, Makinde AY, Andres ML, Coutrakon GB, Koss P, Slater JM, Pecaut MJ. Low dose proton radiation-induced gene expression patterns in CD4+ T helper cells. Presented at DOE Low Dose Radiation Research Investigators’ Workshop VII. Washington, DC. Abstract Book page 83. January 21-23, 2008. ( 1/2008 )
  • Zhang Y, Clement J, Gridley DS, Rodhe L, Wu H. Comparison of protein expression profile changes in human fibroblasts induced by low doses of gamma rays and energetic protons. Presented at DOE Low Dose Radiation Research Investigators’ Workshop VII. Washington, DC. Abstract Book page 163.  January 21-23, 2008. ( 1/2008 )
  • Gridley, D.S., Pecaut, M.J., Coutrakon, G., Rizvi, A., Luo, X., Koss, P., Benton, E., and Slater, J.M. . "Immune modification after a simulated solar particle event with and without low dose photon exposure. ." Conference of the Particle Therapy Co-Operative Group (PTCOG) 45-2006. . (2007): 9-9. ( 10/2007 )
  • Baqai, F., Gridley, D.S., Bayeta, E., Andres, M., Makinde, A., Rizvi, A. Luo, X., and Pecaut, M.J. . "Effects of head only proton radiation on peripheral phagocyte function. ." 14th Annual Meeting of the Psychoneuroimmunology Research Society (PNIRS), Arcachon, France . (2007): Abstract Book p. 28. ( 5/2007 - 6/2007 )
     
  • Baqai, F., Gridley, D.S., Bayeta, E., Andres, M., Makinde, A., Rizvi, A. Luo, X., and Pecaut, M.J. "Effects of head only proton radiation on peripheral phagocyte function." 14th Annual Meeting of the Psychoneuroimmunology Research Society (PNIRS), Arcachon, France. May 30 - June 3 . (2007): 28-. ( 5/2007 )
  • Tian, J. and Gridley, D.S. "Expression of extracellular matrix regulators in lung tissue of mice exposed to different types of radiations." 98th Annual meeting of the American Association for Cancer Research (AACR). Los Angeles, CA. April 14-18 . (2007): -. ( 4/2007 ) Link...
  • Makinde A.Y., Luo, X., Andres, M.L., Slater, J.M., Crapo, J.D., Pearlstein, R.D., and Gridley, D.S. "Prostate cancer response to radiation in the presence of a metalloporphyrin antioxidant." 98th Annual meeting of the American Association for Cancer Research (AACR). Loa Angeles, CA. April 14-18 . (2007): -. ( 4/2007 ) Link...
  • Lin, Q., Schulte, R.W., Luo, X., Andres, M.L., Sila, C.R., Williams, J.R., Slater, J.M., and Gridley, D.S. "Time-sensitive enhancement of human glioma cell killing after treatment with low-dose Adriamycin followed by Co-60 radiation." 53rd Ann. Meeting of the Radiation Research Society in conjunction with American Society For Therapeutic Radiology and Oncology (ASTRO). Philadelphia, PA, Nov. 6-9 . (2006): 100-101. ( 11/2006 )
  • Pecaut, M.J., Baqai, F., Bayeta, E., and Gridley, D.S. "Effects of radiation on macrophage function." Annual Meeting of the American Society for Gravitational and Space Biology (ASGSB). Nov. 2-5. Gravitational Space Biol. 20.1 (2006): 47-. ( 11/2006 )
  • Bateman, T.A., Pecaut, M.J., Bandstra, E.R., Willey J.S., Travis, N.D., Nelson, G.A., and Gridley, D.S. "Space radiation and bone loss ." 22nd Annual Meeting of the American Society for Gravitational and Space Biology (ASGSB). Nov. 2-5. Gravitational Space Biol. 20.1 (2006): 47-. ( 11/2006 )
  • Gridley, D.S., Rizvi, A., Coutrakon, G., Luo, X., Andres, M.L., Lin, Q., Slater, J.M., and Pecaut, M.J. "Variable gene expression after acute whole-body irradiation with photons, protons and simulated solar flare protons." 53rd Ann. Meeting of the Radiation Research Society (RRS) in conjunction with American Society For Therapeutic Radiology and Oncology (ASTRO). Philadelphia, PA, Nov. 6-9 . (2006): 109-. ( 11/2006 )
  • Pearlstein, R.D., Higuchi, Y., Moldovan, M., Gridley, D.S., Warner, D.S., Crapo, J.D., and Slater, J.M. "Effects of a metalloporphyrin antioxidant on radiation injury to the rat brain." 53rd Ann. Meeting of the Radiation Research Society (RRS) in conjunction with American Society For Therapeutic Radiology and Oncology (ASTRO). Philadelphia, PA, Nov. 6-9 . (2006): 84-. ( 11/2006 )
  • Tian, J., Andres, M.L., and Gridley, D.S. "Expression of transforming growth factor-beta1 in lung tissue of mice exposed to different types of radiations." 53rd Ann. Meeting of the Radiation Research Society (RRS) in conjunction with American Society For Therapeutic Radiology and Oncology (ASTRO). Philadelphia, PA, Nov. 6-9. . (2006): 111-. ( 11/2006 )
  • Luo, X., Rizvi, A., Coutrakon, G., Makinde, A.Y., Perez, C., Andres, M.L., Rightnar, S., Slater, J.M., Pecaut. M.J., and Gridley, D.S. "Blood and spleen analyses after whole-body low dose photon and solar flare proton irradiation." 53rd Ann. Meeting of the Radiation Research Society (RRS) in conjunction with American Society For Therapeutic Radiology and Oncology (ASTRO). Philadelphia, PA, Nov. 6-9. . (2006): 109-110. ( 11/2006 )
  • Rizvi, A., Coutrakon, G., Luo, X, Makinde, A.Y., Jian, T, Slater, J.M., Pecaut, M.J., and Gridley, D.S. "Protracted low dose photon and simulated solar flare proton effects on gene expression after whole-body irradiation." 53rd Ann. Meeting of the Radiation Research Society (RRS) in conjunction with American Society For Therapeutic Radiology and Oncology (ASTRO). Philadelphia, PA, Nov. 6-9 . (2006): 109-. ( 11/2006 )
  • Makinde, A.Y., Luo, X., Rizvi, A., Andres, M.L., Slater, J.M., Crapo, J.D., Pearlstein, R.D., and Gridley, D.S. "Metalloporphyrin antioxidant effect on prostate cancer response to radiation." 53rd Ann. Meeting of the Radiation Research Society (RRS) in conjunction with American Society For Therapeutic Radiology and Oncology (ASTRO). Philadelphia, PA, Nov. 6-9 . (2006): 91-. ( 11/2006 )
  • Baqai, F., Bayeta, E., Andres, M., Makinde, A., Rizvi, A, Gridley, D.S., and Pecaut, M.J. "Effects of whole-body proton irradiation on phagocytic function." 53rd Ann. Meeting of the Radiation Research Society (RRS) in conjunction with American Society For Therapeutic Radiology and Oncology (ASTRO). Philadelphia, PA, Nov. 6-9 . (2006): 81-. ( 11/2006 )
  • Willey J.S., Grilly, L.G., Howard, S.H., Pecaut, M.J., Obenaus, A., Gridley, D.S., Nelson, G.A., and Bateman, T.A. "The effects of 56Fe on structural properties and microarchitecture in trabecular and cortical bone." 53rd Ann. Meeting of the Radiation Research Society (RRS) in conjunction with American Society For Therapeutic Radiology and Oncology (ASTRO). Philadelphia, PA, Nov. 6-9 . (2006): 112-. ( 11/2006 )
  • Gridley, D.S., Pecaut, M.J., Coutrakon, G., Rizvi, A., Luo, X., Koss, P., Benton, E., and Slater, J.M. "Immune modification after a simulated solar particle event with and without low dose photon exposure." Presented at Conference of the Particle Therapy Co-Operative Group (PTCOG) 45-2006. Houston, TX. Oct. 7-11 . (2006): -. ( 10/2006 )
  • Coutrakon, G., Benton, E., Gridley, D.S., Hickey, T., Hubbard, J., Koss, P., Moyers, M.F., Pecaut, M.J., Rightnar, S., Shahnazi, K., and Slater, J.M. "Simulation of a 36 hour solar flare using a scanned proton beam on a 1 m x 1m target." 19th Intl. Conference on Applications of Accelerators for Research and Industry (CAARI), Fort Worth, TX. August 20-25 . (2006): THU-MA12-P1-. ( 8/2006 )
  • Gridley, D.S., Rizvi, A., Luo, X., Makinde, A.Y., Rightnar, S., Tian, J., Andres, M.L., Slater, J.M., and Pecaut, M.J. "Low dose photon radiation-induced changes in T helper lymphocytes." DOE Low Dose Radiation Research Program Workshop VI, Washington, D.C. Sponsored by U.S. Dept. of Energy Office of Biological and Environmental Research. July 31-Aug. 2 . (2006): 65-. ( 7/2006 )
  • Rizvi, A., Coutrakon, G., Slater, J.M., Pecaut, M.J., and Gridley, D.S. "Protracted low dose photon and simulated solar flare proton effects on cytokine/chemokine expression after whole-body irradiation." DOE Low Dose Radiation Research Program Workshop VI, Washington, D.C. Sponsored by U.S. Dept. of Energy Office of Biological and Environmental Research. July 31-Aug. 2 . (2006): 67-68. ( 7/2006 )
  • Luo, X., Makinde, A.Y., Rizvi, A., Crapo, J.D., Slater, J.M., Pearlstein, R.D., Pecaut, M.J., and Gridley, D.S. "Enhanced DNA response following whole-body irradiation plus treatment with an antioxidant mimetic."  Presented at 97th Ann. Meeting of the American Association for Cancer Research (AACR). Washington, D.C., April 1-5, 2006  47:1037, 2006 ( 7/2005 - 6/2006 )
     
  • Luo, X., Makinde, A.Y., Rizvi, A., Crapo, J.D., Slater, J.M., Pearlstein, R.D., Pecaut, M.J., and Gridley, D.S. "Enhanced DNA response following whole-body irradiation plus treatment with an antioxidant mimetic." Proceedings of the American Association for Cancer Research 47. (2006): 1037-1037. ( 4/2006 )
  • Komorowska-Timek, E., Oberg, K.C., Timek, T.T., Gridley D.S., and Miles, D. "Characteristics of peri-prosthetic Alloderm envelopes in a rat implant model." The Aesthetic Meeting 2006. American Society for Aesthetic Plastic Surgery and Aesthetic Surgery Education & Research Foundation (ASAPS/ASERF) Residents & Fellows Forum, Meeting Abstract Book . (2006): -. ( 4/2006 )
  • Tian, J. and Gridley, D.S. . "Expression of extracellular matrix regulators in lung tissue of mice exposed to different types of radiations. 98th Annual meeting of the American Association for Cancer Research (AACR). Los Angeles, CA.." . (2006): -. ( 4/2006 ) Link...
  • Komorowska-Timek, E., Oberg, K.C., Timek, T.A., Gridley, D.S., and Miles, D. "The effect of Seprafilm envelopes on peri-prosthetic capsule formation in the rat radiated implant model." Plastic Surgery Senior Residents Conference, Meeting Abstract Book . (2006): -. ( 3/2006 )
  • Carter, J.L., Molinaro, C.A., Damjanovic, A.K., Vyas, S., Gridley, D.S., ThyagaRajan, S., and Bellinger, D.L. "Sympathetic modulation of mammalian cancer in vitro." 13th Annual Meeting of the Psychoneuroimmunology Society (PNIRS), Meeting Abstract Book . (2006): 8-9. ( 1/2006 )
  • Luo X., Kim, D.W., Crapo, J.D., Pearlstein, R. Slater, J.M., and Gridley, D.S. "Differential modification of tumor and normal cell response to radiation by a metalloporphyrin antioxidant." 52nd Annual Meeting of the Radiation Research Society (RRS), Meeting Abstract Book . (2005): -. ( 10/2005 )
  • Hamilton, S.A., Gridley, D.S., Pecaut, M.J., Harris, L.G., Howard, H.S., and Bateman, T.A. "Osteoblast and osteoclast response to radiation induced bone loss." 52nd Ann. Meeting of the Radiation Research Society (RRS), Meeting Abstract Book . (2005): -. ( 10/2005 )
  • Hamilton, S.A., Gridley, D.S., Pecaut, M.J., Harris, L.G., Howard, H.S., and Bateman, T.A.. "Low dose ionizing radiation induces murine bone loss." Abstract Book: Bone Loss During Spaceflight: Etiology, Countermeasures, and Implications for Bone Health on Earth Symposium . (2005): 361-361. ( 6/2005 )
  • Damjanovic, A.K., Carter, J., Gridley, D.S., ThyagaRajan, S., Molinaro, C., and Bellinger, D.L. "Sympathetic modulation of mammalian prostate cancer." Abstract Book: 12th Ann. Mtg. of PNIRS . (2005): 13-13. ( 6/2005 )
  • Hamilton, S.A., Pecaut, M.J., Gridley, D.S., and Bateman, T.A.. "Effects of radiation on murine bone loss.." Abstract Book: 15th Mtg. Intl. Acad. Aeronaut. (IAA) . (2005): 85-85. ( 5/2005 )
  • Gridley, D.S., Bateman, T., Hamilton, S.A., Obenaus, A., and Pecaut, M.J. "Long-term effects of whole-body, high-LET radiation on blood chemistry.." Abstract Book: 16th Ann. Mtg. NASA Space Radiat. Investig. Workshop . (2005): 69-69. ( 5/2005 )
  • Gridley, D.S., Green, L.M., Slater, J.M., and Pecaut, M.J.. "Mechanisms of low dose radiation-induced T helper cell function.." Abstract Book: DOE Low Dose Radiat. Res. Program Workshop . (2005): 59-59. ( 1/2005 )
  • Rizvi, A., Makinde, A.Y., Pecaut, M.J., and Gridley, D.S.. "Protracted total-body irradiation modulates leukocyte response to acute radiation exposure." Proc. of Amer. Assoc. for Cancer Res. (AACR) 46. (2005): 288-288. ( 1/2005 )
  • Luo, X., Andres, M.L., Slater, J.M., and Gridley, D.S.. "Combined effects of radiation and endostatin gene therapy on leukocyte, erythrocyte, and thrombocyte populations in a lung carcinoma model." Proc. of Amer. Assoc. for Cancer Res. (AACR) 46. (2005): 790-790. ( 1/2005 )
  • Makinde, A.Y., Rizvi, A., Luo, X., Andres, M.L., Archambeau, J.O., Pearlstein, R.D., James M. Slater, J.M., and Gridley, D.S.. " Effects of AEOL 10150 on prostate tumor response to radiation.." Proc. of Amer. Assoc. for Cancer Res. (AACR) 46. (2005): 466-466. ( 1/2005 )
  • Luo X., Kim, D.W., Crapo, J.D., Pearlstein, R. Slater, J.M., and Gridley, D.S. "Differential modification of tumor and normal cell response to radiation by a metalloporphyrin antioxidant." 52nd Ann. Meeting of the Radiation Research Society (RRS) . (2005): -. ( 1/2005 )
  • Luo X., Kim, D.W., Crapo, J.D., Pearlstein, R. Slater, J.M., and Gridley, D.S. "Differential modification of tumor and normal cell response to radiation by a metalloporphyrin antioxidant." 52nd Annual Meeting of the Radiation Research Society (RRS) . (2005): -. ( 1/2005 )
  • Pearlstein, R.D., Moldovan, M., Nie, Y., Gridley, D.S., Slater, J.B., and Slater, J.M. "PK-11195 binding increases in the pilocarpine model of spontaneous recurrent seizures: Relationship to seizure frequency.." Abstract Book: 34th Ann. Mtg. of the Soc. Neurosci. . (2004): 451-451. ( 7/2004 )
  • Gridley, D.S., Timiryasova, T.M., Chen, B., Andres, M.L., Dutta-Roy, R., Miller, G., Bayeta, E.J.M., and Fodor, I. "Combination with p53 gene therapy enhances the antitumor effect of radiation in a glioma model.." Central European J. Occupat. and Environ. Med. (CEJOEM 10. (2004): S70-S70. ( 7/2004 )
  • Gridley, D.S., Obenaus, A., and Pecaut, M.J.. "Chronic hematological and lymphoid effects after high-LET, high-energy iron ion irradiation." Abstract Book: Am. Soc. Gravitational and Space Biol. (ASGSB) 18.1 (2004): 63-63. ( 7/2004 )
  • Pecaut, M.J., Green, L.M., Bianski, B., Jones, T.A., Nelson, G.A., Kostenuik, P.J., Bateman, T.A., Morony, S., Stodieck, L.S., Lacey, D.L., Simske, S.J., and Gridley, D.S.. " Effects of spaceflight on hepatic gene expression in the C57BL/6 mouse.." Gravitational and Space Biology Bulletin 18.1 (2004): 56-56. ( 7/2004 )
  • Harris, L.G., Pecaut, M.J., Nelson, G.A., Gridley, D.S., and Bateman, T.A.. "The effects of radiation on the rat bone." Gravitational and Space Biology Bulletin 18.1 (2004): 20-20. ( 7/2004 )
  • Pearlstein, R.D., Moldovan, M., Nie, Y., Gridley, D.S., Slater, J.B., and Slater, J.M. "PK-11195 binding increases in the pilocarpine model of spontaneous recurrent seizures: Relationship to seizure frequency.." Abstract Book: 34th Ann. Mtg. of the Soc. Neurosci. . (2004): 451-451. ( 6/2004 )
  • Damjanovic, A.K., Carter, J., Gridley, D.S., ThyagaRajan, S., Molinaro, C., and Bellinger, D.L.. " Sympathetic Modulation of Mammalian Prostate Cancer." Abstract Book: 12th Ann. Meeting of the Psychoneuroimmunology Society (PNIRS) . (2004): 13-13. ( 6/2004 )
  • Damjanovic, A.K., Carter, J., Gridley, D.S., ThyagaRajan, S., Molinaro, C., and Bellinger, D.L.. " Sympathetic Modulation of Mammalian Prostate Cancer." Abstract Book: 12th Ann. Meeting of the Psychoneuroimmunology Society (PNIRS) . (2004): 13-13. ( 6/2004 )
  • Damjanovic, A.K., Carter, J., Gridley, D.S., ThyagaRajan, S., Molinaro, C., and Bellinger, D.L.. "Sympathetic modulation of mammalian prostate cancer.." Abstract Book: 12th Ann Meeting of the Psychoneuroimmunology Society (PNIRS) . (2004): 13-13. ( 6/2004 )