John Rossi, PhD Adjunct Professor, Basic Sciences School of Medicine

Publications 

  Scholarly Journals--Published

• 1. Gu, S. and Rossi, J.J.. "Uncoupling of RNAi from active translation in mammalian cells." RNA 11. (2005): 38-44. ( 1/2005 )

• 1. Kim, D.-H., Behlke, M.A., Rose, S.D. and Rossi, J.J.. "Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy." Nature Biotech. 23. (2005): 222-226. ( 1/2005 )

• 1. Weinberg, M. and Rossi, J.J.. "Comparative single-turnover kinetic analyses of trans-cleaving hummerhead ribozymes and naturally derived non-conserved sequence motifs." FEBs Lett. 579. (2005): 1619-1624. ( 1/2005 )

• 1. Soifer, H.S., Zaragoza, A., Peyvan, M., Behlke, M. and Rossi J.J.. "A potential role for RNA interference in controlling the activity of the humann LINE-1 retrotransposon." Nucl. Acid. Res. 33. (2005): 846-856. ( 1/2005 )

• 1. Heale, B., Bowers, D., Soifer, H.S. and Rossi, J.J.. "siRNA target site secondary structure predictions using local stable substructures." Nucl. Acid Res. 33. (2005): e30-. ( 1/2005 )

• 1. Robbins, M.A. and Rossi, J.J.. "Sensing the danger in RNA." Nature Med. 11. (2005): 250-251. ( 1/2005 )

• 1. Gonzalez, S., Castnaotto, D., Li, J., Oliveres, S., Jensen, M.D., Forman, S.J., Rossi, J.J. and Cooper, L.J.N.. "Amplification of RNAi-Targeting HLA mRNAs." Mol. Ther. 11. (2005): 811-818. ( 1/2005 )

• 1. Rossi, J.J.. "News and Views: Receptor-targeted siRNAs - Protamine-antibody fragment fusions enable delivery of siRNAs to specific cells in mice." Nature Biotech. 23. (2005): 682-684. ( 1/2005 )

• 1. Cook, H.L., Lytle, J.R., Mischo, H.E, Li, M.-J., Rossi, J.J., Silva, D.P., Desrosiers, R.C. and Steitz, J.A. . "Small nuclear RNAs encoded by Herpesvirus saimiri upregulate the expression of genes linked to T cell activation in virally transformed T cells." Current Biol. 15. (2005): 974-979. ( 1/2005 )

• 1. Castanotto, D., Tommasi, S., Li, M., Li, H., Yanow, S., Pfeifer, G.P. and Rossi, J.J.. "Short hairpin RNA directed cytosine (CpG) methylation of the RASSFIA gene promoter in HeLa cells." Mol. Ther. 12. (2005): 179-183. ( 1/2005 )

• 1. Strayer, D.S., Akkina, R., Bunnell, B.A., Dropulic, B., Planelles, V., Pomerantz, R.J., Rossi, J.J. and Zaia, J.A.. "Current Status of Gene Therapy Strategies to Treat HIV/AIDS." Mol. Ther. 11. (2005): 823-842. ( 1/2005 )

• 1. Rossi, J.J.. "Mammalian Dicer Finds a Partner." EMBO J. 6. (2005): 927-929. ( 1/2005 )

• 1. Scherer, L.J., Yildiz, Y., Kim, J., Cagnon, L., Heale, B. and Rossi J.J. . "Rapid Assessment of anti-HIV Efficacy using PCR-derived Pol III shRNA cassettes." Mol. Ther. 10. (2004): 597-603. ( 1/2004 )

• 1. Scherer, L.J. and Rossi, J.J.. "Recent applications of RNAi in mammalian systems." Curr. Pharm. Biotechnol. 5. (2004): 355-360. ( 1/2004 )

• 1. Cordelier, P., Kulkowsky, W., Ko, C., Matskevitch, A.A.., McKee, H.J., Rossi, J.J., Bouhamdan, M., Pomerantz, R.J., Kari, G., Strayer, D.S. . "Protecting from R5-tropic HIV: individual and combines effectiveness of a hammerhead ribozyme and a single-chain Fv antibody that targets CCR5." Gene Ther. 11. (2004): 1627-1637. ( 1/2004 )

• 1. Scherer, L.J. and Rossi J.J.. "RNAi applications in mammalian cells." Biotechniques 11. (2004): 557-561. ( 1/2004 )

• 1. Hannon, G.J. and Rossi, J.J.. "Unlocking the potential of the human genome with RNA interference." Nature 431. (2004): 371-378. ( 1/2004 )

• 1. Song, J., Lu, Y.C., Yokoyama, K.K., Rossi, J.J. and Chiu, R. . "Cyclophilin A is required for retinoic acid-induced neuronal differentiation in p19 cells." J. Biol. Chem. 279. (2004): 24424-24429. ( 1/2004 )

• 1. Unwalla, H., Li., J.-J., Kim, J.D., Li, H.T., Ehsani, A., Alluin, J. and Rossi, J.J.. "Negative feedback inhibition of HIV-1 by TAT-inducible expression of siRNA." Nature Biotech. 22. (2004): 1573-1578. ( 1/2004 )

• 1. Rossi, J.J.. "Ribozyme Diagnostics Comes of Age." Chem. Biol. 11. (2004): 894-895. ( 1/2004 )

• 1. Rossi, J.J.. "Medicine: a cholesterol connection in RNAi." 432. (2004): 155-156. ( 1/2004 )

• 1. Banerjea, A., Li, M.-J., Remling, L., Rossi, J.J. and Akkina, R.. "Lentiviral transduction of Tar Decly and CCR5 ribozyme into CD34+ progenitor cells and derivation of HIV-1 resistant T cells and macophages." AIDS Res. and Ther. 1. (2004): 2-. ( 1/2004 )

• 1. Scherer, L.J. and Rossi, J.J.. "Recent applications of RNA interference (RNAi) in mammalian systems." Letters in Peptide Sci. 10. (2004): 255-267. ( 1/2004 )

  Books and Chapters

• 1. Li, M.-J., and Rossi, J.J.. Lentiviral Vector Delivery of siRNA and shRNA Encoding Genes into Cultured and Primary Hematopoietic Cells. Totowa, NJ: Humana Press Inc., 2005. ( 1/2005 )

• 2. Scherer, L.J. and Rossi J.J.. Recent Applications of RNA Interference (RNAi) in Mammalian Systems. the Netherlands: Kluwer Academic/Plenum Publishers, 2005. ( 1/2005 )

• 2. Morris, K.V. and Rossi, J.J.. Combinatorial RNA-based Therapies for HIV-1. Weinheim, Germany: Wiley-VCH Verlag , 2005. ( 1/2005 )

• 2. Morris, K.V. and Rossi, J.J.. Lentiviral-mediated RNAi for Antiviral Therapy. Heidelberg, Germany: Springer-Verlag, 2005. ( 1/2005 )

• 1. Engleke, D.R. and Rossi, J.J.. In Methods in Enzymology, RNA Interference. : Elsevier Inc., 2005. ( 1/2005 )

• 1. Castanotto, D. and Rossi, J.J.. Construction and Transffection of PCR Products Expressing siRNAs or shRNAs in Mammalian Cells. Totowa, NJ: Humana Press Inc., 2005. 509 - 514 ( 1/2005 )

• 1. Rossi, J.J.. Therapeutic applications of ribozymes. Totowa, NJ: Humana Press Inc., 2004. 45 - 64 ( 1/2004 )

• 1. Zaia, J.J., Cairns, J.S. and Rossi, J.J.. AIDS and Hematopoietic Transplatation: HIV Infection, AIDS Lymphoma, and Gene Therapy. Malden, MA: Blackwell Science Inc., . 1369 - 1384 (*)

• 1. Scherer, L.J., and Rossi J.J.. Therapeutic aplications of RNA interference: recent advances in siRNA design. San Diego, CA: Elsevier Inc., . 1 - 21 (*)