Loma Linda University

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Chandrasekhar Kesavan, PhD
Asst Res Prof, Medicine
School of Medicine
Publications    Scholarly Journals--Published
    • Yu H, Watt H, Kesavan C, Mohan S. The negative impact of single prolonged stress (SPS) on bone development in mice. Stress, May 20, 2013.
    • Anthony S, Santisuk R, Xing W and Kesavan C. Systemic Administration of an Antagomir Designed to inhibit miR-92, a Regulator of Angiogenesis, Failed to Modulate Skeletal Anabolic Response to Mechanical Loading. Physiol. Res, 16; 62 (2), 221-6, 2013.
    • Anthony S, Mohan S and Kesavan C: Bone response to loading in mice with targeted disruption of the cartilage oligomeric matrix protein gene, Physiological Research Oct 12, 2012.
    • Nagamani S, Kesavan C and Karthikeyan M. E-Pharmacophore mapping and dockingstudies on Vitamin D receptor (VDR). Bioinformation, 8(15):705-10, 2012.
    • Yu H, Watt H, Kesavan C, Johnson PJ, Wergedal JE, Mohan S. Lasting consequences of traumatic events on behavioral and skeletal parameters in a mouse model for post-traumatic stress disorder (PTSD). PLoS One,7(8):e42684, 2012.
    • Mohan S, Kesavan C. Role of insulin-like growth factor-1 in the regulation of skeletal growth. Curr Osteoporos Rep. 2012 Jun;10(2):178-86, 2012, Review.
    • Xing W, Govoni KE, Donahue LR, Kesavan C, Wergedal J, Long C, Bassett JH, Gogakos A, Wojcicka A, Williams GR, Mohan S. Genetic evidence that thyroid hormone is indispensable for prepubertal insulin-like growth factor-I expression and bone acquisition in mice. J Bone Miner Res.May;27(5):1067-7, 2012.
    • Cheng S, Zhao SL, Nelson B, Kesavan C, Qin X, Wergedal J, Mohan S, Xing W. Targeted disruption of ephrin B1 in cells of myeloid lineage increases osteoclast differentiation and bone resorption in mice. PLoS One,7(3):e32887, 2012.
    • Kesavan C, Mohan S. Bone mass gained in response to external loading is preserved for several weeks following cessation of loading in 10 week C57BL/6J mice. J Musculoskelet Neuronal Interact, 10 (4): 247-80, 2010.
    • Kesavan C, Mohan S. Bone mass gained in response to external loading is preserved for several weeks following cessation of loading in 10 week C57BL/6J mice. J Musculoskelet Neuronal Interact,10(4):274-80, 2010.
    • Kapur S, Amoui M, Kesavan C, Wang X, Mohan S, Baylink DJ, Lau KH. Leptin receptor (Lepr) is a negative modulator of bone mechanosensitivity and genetic variations in Lepr may contribute to the differential osteogenic response to mechanical stimulation in the C57BL/6J and C3H/HeJ pair of mouse strains. J Biol Chem,285(48):37607-18, 2010.
    • Kesavan C, Mohan S. Lack of anabolic response to skeletal loading in mice with targeted disruption of the pleiotrophin gene. BMC Res Notes, 1:124, 2008.
    • Johnson IM, Kesavan C, Usha S, Malathi R. Analysis of group I intron splicing in the presence of naturally occurring methylxanthines. Clin Chim Acta, 74-6, 2009.
    • Kesavan C, Baylink DJ, Kapoor S, Mohan S. Novel loci regulating bone anabolic response to loading: expression QTL analysis in C57BL/6JXC3H/HeJ mice cross. Bone, 41(2):223-30, 2007.
    • Kesavan C, Mohan S, Srivastava AK, Kapoor S, Wergedal JE, Yu H, Baylink DJ. Identification of genetic loci that regulate bone adaptive response to mechanical loading in C57BL/6J and C3H/HeJ mice intercross. Bone,39(3):634-43, 2006.
    • Lau KH, Kapur S, Kesavan C, Baylink DJ. Up-regulation of the Wnt, estrogen receptor, insulin-like growth factor-I, and bone morphogenetic protein pathways in C57BL/6J osteoblasts as opposed to C3H/HeJ osteoblasts in part contributes to the differential anabolic response to fluid shear. J Biol Chem, 281(14):9576-88, 2006.
    • Kesavan C, Joyee AG. 5-fluorouracil altered morphology and inhibited growth of Candida albicans. J Clin Microbiol, 43(12):6215-6, 2005.
    • Xing W, Baylink D, Kesavan C, Hu Y, Kapoor S, Chadwick RB, Mohan S. Global gene expression analysis in the bones reveals involvement of several novel genes and pathways in mediating an anabolic response of mechanical loading in mice. J Cell Biochem, 96(5):1049-60, 2005.
    • Kesavan C, Mohan S, Oberholtzer S, Wergedal JE, Baylink DJ. Mechanical loading-induced gene expression and BMD changes are different in two inbred mouse strains. J Appl Physiol,99(5):1951-7, 2005.
    • Kesavan C, Raghunathan M, Ganesan N. Morphological and growth altering effects of Cisplatin in C. albicans using fluorescence microscopy. Ann Clin Microbiol Antimicrob,4:7, 2005.