Hansel Fletcher, PhD Vice Chair, Basic Sciences, Microbiology Division School of Medicine Professor, Basic Sciences School of Medicine Professor, Periodontics School of Dentistry Member, Microbiology&Molecular Gen, SM, Faculty of Graduate Studies

Research & Grantsmanship 

  Funded Research Project (PI)

• National Institute of Health, National Institute for Dental Research. "Studies on virulence regulation in Porphyromonas ", H. M. Fletcher, Principal Investigator. Total budget $1,946,367.  3/15/07 - 3/14/12 (2 RO1 DE13664). ( 3/2006 - 2/2012 )

  Abstracts Reporting Research -- Peer Reviewed

• Osbourne, D., W. Aruni, Y. Dou, A. Muthiah, C. Perry and H. M. Fletcher. Nanoscale organization of peptidoglycan in Porphyromonas gingivalis. Seeing at the Nanoscale Conference, UC Santa Barbara July 2011. ( 7/2011 )

• Aruni, W. and H. M. Fletcher. Epithelial cell invasion by Filifactor alocis is enhanced by Porphyromonas. Rochester Conference on Oral Biology: Post-Genomics for the Oral Microbiome. Rochester, NY, June 2011. (Award winning). ( 6/2011 )

• Robles, A., and H. M. Fletcher. VimA‘s effect on the Glycosylation of RgpB from Porphyromonas gingivalis. International Association for Dental Research, San Diego, March 2011. ( 3/2011 )

• Aruni, W., J. Lee, D. Osbourne, F. Roy, A. Muthiah, H. M. Fletcher. Elucidating the role of VimA in Porphyromonas gingivalis through in silico and proteomic studies.   International Association for Dental Research, San Diego, March 2011. ( 3/2011 )

• Muthiah, A., W. Aruni, D. Osbourne and H. M. Fletcher. VimF, a putative glycosyltranferase, is localized on outer membrane and membrane vesicles in Porphyromonas gingivalis W83. International Association for Dental Research, San Diego, March 2011. ( 3/2011 )

• Muthiah, A., W. Aruni, D. Osbourne and H. M. Fletcher. VimF, a putative glycosyltranferase, is localized on outer membrane and membrane vesicles in Porphyromonas gingivalis W83. International Association for Dental Research, San Diego, March 2011. ( 3/2011 )

• Henry, L. G. and H. M. Fletcher. Protective role of the uvrA-pg1037-uvrD operon in oxidative stress defense in Porphyromonas gingivalis W83. International Association for Dental Research, San Diego, March 2011. ( 3/2011 )

• Yuetan D., F. Roy, D. Osbourne, W. Aruni and H. M. Fletcher. The role of RgpB in late onset gingipain activity in the vimA-defective mutant of Porphyromonas gingivalis W83. International Association for Dental Research, San Diego, March 2011. ( 3/2011 )

• Osbourne, D.,  W.Aruni, Y. Dou, A. Muthiah, F.Roy and H. M. Fletcher. The VimA of Porphyromonas gingivalis is a putative acyl transferase. International Association for Dental Research, San Diego, March 2011. ( 3/2011 )

  Abstracts Reporting Research -- Non-Peer Reviewed

• National Institute of Health, National Institute for Dental Research. "Mechanisms for adaptation to oxidative stress in Porphyromonas gingivalis", H. M. Fletcher, Principal Investigator. Total budget $1,806,625. 06/08/2009 – 03/31/2014 (1 R01 DE019730). ( 4/2011 - 3/2012 )

• Boutrin, M-C and H. M. Fletcher. Studies on the involvement of PG0893 and PG2213 in Nitric Oxide stress resistance in Porphyromonas gingivalis. International Association for Dental Research, San Diego, March 2011 ( 3/2011 )