Loma Linda University

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Jiping Tang, MD
Professor, Basic Sciences
School of Medicine
Member, Physiology, SM, Faculty of Graduate Studies
Publications    Book Review - Scholarly Journals--Published
  • Titova E, Ostrowski RP, Zhang JH, Tang J. Experimental models of subarachnoid hemorrhage for studies of cerebral vasospasm. Journal of Neurological Research. 31:568-581, 2009 ( 0/2009 )
  Scholarly Journals--Published
  • Wu B, Ma Q, Suzuki H, Chen C, Liu W, Tang J, Zhang J. Recombinant Osteopontin Attenuates Brain Injury after Intracerebral Hemorrhage in Mice. Neurocritical Care, 14:109-117, 2011 ( 0/2011 )
  • Ma Q, Manaenko A, Khatibi N, Chen W, Zhang JH, Tang J. Vascular adhesion protein-1 inhibition provides neuroprotection from intracerebral hemorrhage induced brain injury in mice. Journal of Cerebral Blood Flow & Metabolism, 31:881-893, 2011 ( 0/2011 )
  • Lekic T, Rolland W, Hartman R, Kamper J, Suzuki H, Tang J, Zhang JH. Characterization of the Brain Injury, Neurobehavioral Profiles and Histopathology in a Rat Model of Cerebellar Hemorrhage. Experimental Neurology, 227:96-103, 2011 ( 0/2011 )
  • Chen W, Ma Q, Suzuki H, Hartman R, Tang J, Zhang JH, Osteopontin reduced hypoxia-ischemia neonatal brain injury by suppression of apoptosis in a rat pup model, Stroke, 42:764-769, 2011 ( 0/2011 )
  • Hu Q, Ma Q, Zhan Y, He Z, Zhou C, Tang J, Zhang JH. Isoflurane Enhanced Hemorrhagic Transformation by Impairing Antioxidant Enzymes in Hyperglycemic MCAO Rats. Stroke, 42:1750-1756, 2011 ( 0/2011 )
  • Manaenko A, Chen H, Kammer J, Zhang JH, Tang J. Comparison Evans Blue Injection Routes: Intravenous vs. Intraperitoneal, for Measurement of Blood-Brain Barrier in a Mouse Hemorrhage Model. Journal of Neuroscience Methods. 195:206-210, 2011 ( 0/2011 )
  • Duris K, Manaenko A, Suzuki H, Rolland W, Tang J, Zhang JH. Sampling of CSF via the Cisterna Magna and Blood Collection via the Heart Affects Brain Water Content in a Rat SAH Model. Translational Stroke Research. 2:232-237, 2011 ( 0/2011 )
  • Manaenko A, Fathali N, Khatibi N, Lekic T, Hasegawa Y, Tang J, Zhang JH. Arginine- Vasopressin V1a Receptor Inhibition Improves Neurologic Outcomes Following An Intracerebral Hemorrhagic Brain Injury. Neurochemistry International. 58:542-548, 2011 ( 0/2011 )
  • Khatibi N, Ma Q, Rolland W, Ostrowski R, Fathali N, Martin R, Applegate R, Stier G, Tang J, Zhang J. Isoflurane post-treatment reduces brain injury following intracerebal hemorrhagic stroke in mice. Anesthesia & Analgesia. 2011 May 19. PMID: 21506881 ( 0/2011 )
  • Chen D, Tang J, Khatibi NH, Zhu M, Li Y, Wang C, Jiang R, Tu L, Wang S. Treatment with z-ligustilide, a component of angelica sinensis, reduces brain injury following a subarachnoid hemorrhage in rats. The Journal of pharmacology and experimental therapeutics. 337:663-672, 2011 ( 0/2011 )
  • Eckermann J, Chen W; Jadhav V, Frank H; Colohan A, Tang J, Zhang J. Hydrogen is Neuroprotective against Surgically Induced Brain Injury. Medical Gas Research. 1:7, 2011 ( 0/2011 )
  • Fathali N, Ostrowski RP, Lekic T, Jadhav V, Tong W, Tang J, Zhang JH. Cyclooxygenase-2 inhibition provides lasting protection against neonatal hypoxic-ischemic brain injury, Critical Care Medicine, 38:572-578, 2010 ( 0/2010 )
  • Wu B, Ma Q, Khatibi N, Chen W, Sozen T, Cheng O, Tang J. Ac-YVAD-CMK Decreases Blood Brain Barrier Degradation by Inhibiting Caspase-1 Activation of Interleukin 1β in Intracerebral Hemorrhage Mouse Model. Translational Stroke Research, 1:57-64, 2010 ( 0/2010 )
  • Tong W, Chen W, Ostrowski RP, Ma Q, Souvenir R, Zhang L, Zhang JH, Tang J. Maternal hypoxia increases the activity of MMPs and decreases the expression of TIMPs in the brain of neonatal rats. Developmental Neurobiology, 70:182-194, 2010 ( 0/2010 )
  • Chen C, Ostrowski RP, Zhou C, Tang J, and Zhang JH. Suppression of Hypoxia-Inducible Factor-1a and Its Downstream Genes Reduces Acute Hyperglycemia-Enhanced Hemorrhagic Transformation in a Rat Model of Cerebral Ischemia. Journal of Neuroscience Research, 88:2046-2055, 2010 ( 0/2010 )
  • Chen C, Manaenko A, Zhan Y, Liu W, Ostrowski RP, Tang J, and Zhang JH. Hydrogen Gas Reduced Acute Hyperglycemia‐Enhanced Hemorrhagic Transformation in a Focal Ischemia Rat Model. Neuroscience, 169:402-414, 2010 ( 0/2010 )
  • Fathali N, Lekic T, Zhang JH, Tang J. Long-term evaluation of granulocyte-colony stimulating factor on hypoxic-ischemic brain damage in infant rats. Intensive Care Medicine, 36:1602-1608, 2010 ( 0/2010 )
  • Lekic T, Hartman R, Rojas H, Manaenko A, Chen W, Ayer R, Tang J, Zhang JH. Protective effect of melatonin upon neuropathology, striatal function, and memory ability after intracerebral hemorrhage in rats. Journal of Neurotrauma. 27:627-37, 2010 ( 0/2010 )
  • Li Y, Tang J, Khatibi N, Zhu M, Chen D, Zheng W and Wang S. Ginsenoside RB1 Reduces Neurologic Damage is Anti-Apoptotic, and Down-Regulates p53 and BAX in Subarachnoid Hemorrhage.  Current Neurovascular Research, 7:85-94, 2010 ( 0/2010 )
  • Manaenko A, Fathali N, Chen H, Suzuki H, Williams S, Zhang JH, Tang J. Heat Shock Protein 70 Upregulation by Geldanamycin Reduces Brain Injury in a Mouse Model of Intracerebral Hemorrhage.  Neurochemistry International, 57:844-850, 2010 ( 0/2010 )
  • Hartman R, Lekic T, Rojas H, Tang J, and Zhang JH. Assessing functional outcomes following intracerebral hemorrhage in rats. Brain Research, 1280:148-157, 2009 ( 0/2009 )
  • Chen W, Hartman R, Ayer R, Marcantonio S, Kamper J, Tang J,  Zhang JH. Matrix Metalloproteinases inhibition provides Neuroprotection against Hypoxia-ischemia in the Developing Brain. J Neurochem 111(3): 726-736, 2009   ( 0/2009 )
  • Manaenko A, Lekic T, Sozen T, Tsuchiyama R, Zhang JH, Tang J. Effect of Gap Junction Inhibition on Intracerebral Hemorrhage-Induced Brain Injury in Mice. Journal of Neurological Research, 31:173-178, 2009 ( 0/2009 )
  • Tsuchiyama R, Sozen T, Manaenko A, Zhang JH, Tang J. The Effects of Nicotinamide Adenine Dinucleotide on Intracerebral Hemorrhage-Induced Brain Injury in mice. Journal of Neurological Research, 31:179-182, 2009 ( 0/2009 )
  • Zhou Y, Fathali N, Lekic T, Tang J, Zhang JH. Glibenclamide improves neurological function in neonatal hypoxia-ischemia in rats. Brain Research. 1270:131-139, 2009 ( 0/2009 )
  • Ostrowski R, Graupner G, Titova E, Zhang J, Chiu J, Dach N, Corleone D, Tang J, Zhang JH. The hyperbaric oxygen preconditioning-induced brain protection is mediated by a reduction of early apoptosis after transient global cerebral ischemia. Neurobiology of Disease. 29:1-13, 2008 ( 0/2008 )
  • Bravo TP, Matchett GA, Jadhav V, Martin RD, Jourdain A, Zhang JH, Tang J. Role of Histamine in Brain Protection in Surgical Brain Injury in Mice. Brain Res. 1205:100-107, 2008 ( 0/2008 )
  • Titova E, Ostrowski R, Kevil C, Tong W, Rojas H, Sowers L, Zhang JH, Tang J. Reduced brain injury in CD18 deficient mice after experimental intracerebral hemorrhage. Journal of Neuroscience Research, 86:3240-3245, 2008 ( 0/2008 )
  • Chen W, Jadhav V, Tang J, Zhang JH. HIF-1α inhibition ameliorates neonatal brain injury in a rat pup hypoxic-ischemic model. Neurobiology of Disease. 31:433-41, 2008 ( 0/2008 )
  • Lee S, Jadhav V, Ayer RE, Rojas H, Hyong A, Lekic T, Tang J, Zhang JH. Dual effects of melatonin on oxidative stress after surgical brain injury in rats. J Pineal Res. 46:43-8, 2008 ( 0/2008 )
  • Hyong A, Jadhav V, Lee S, Tong W, Rowe J, Zhang JH, Tang J. Rosiglitazone, a PPAR gamma agonist, attenuates inflammation after surgical brain injury in rodents. Brain Res. 1215:218-224, 2008 ( 0/2008 )
  • Chen W, Jadhav V, Tang J, Zhang J. HIF-1α Inhibition Ameliorates Neonatal Brain Damage after Hypoxic-ischemic Injury. Acta Neurochirurgica Supplemet. 102:395-399, 2008 ( 0/2008 )
  • Lo W, Bravo T, Jadhav V, Zhang JH, Tang J. NADPH Oxidase Inhibition Improves Neurological Outcomes in Surgically-Induced Brain Injury. Neuroscience letters, 414/3:228-232, 2007 ( 0/2007 )
  • Yata K, Matchett G, Tsubokawa T, Tang J, Kanamaru K, Zhang JH. Granulocyte-coloney stimulating factor inhibits apoptotic neuron loss after neonatal hypoxia-ischemia in rats. Brain Res, 1145:227-238, 2007 ( 0/2007 )
  • Titova E, Ostrowski R, Sowers L, Zhang JH, and Tang J. Effects of Apocynin and Ethanol on Intracerebral Haemorrhage-Induced Brain Injury in Rats. CEPP, 34:845-850, 2007 ( 0/2007 )
  • Liu S, Tang J, Ostrowski R, Titova E, Monroe C, Chen W, Lo W, Martin R, and Zhang JH. Oxidative Stress after Subarachnoid Hemorrhage in gp91phox Knockout Mice. Can J Neurol Sci. 34:356-361, 2007 ( 0/2007 )
  • Ostrowski R, Tang J, Zhang HJ. Hyperbaric oxygen suppresses NADPH oxidase in a rat subarachnoid hemorrhage model. Stroke, 37:1314-1318, 2006 ( 0/2006 - 0/2007 )
  • Tang J, Kusaka I, Massey RA, Rollins S, Zhang JH. Increased RhoA Translocation in Aorta of Diabetic Rats. Acta Pharmacologia Sinica, 27:543-548, 2006 ( 0/2006 )
  • Smelley C, Specian RD, Tang J, Zhang JH. Acute gastric changes after intracerebral hemorrhage in rats. Brain Res. 1038:198-207, 2005 ( 0/2005 )
  • Tang J, Liu J, Zhou C, Ostanin D, Grisham M, Granger DN, Nanda A, Zhang JH. Role of NADPH Oxidase in the Brain Injury of Intracerebral Hemorrhage. J Neurochem.  94:1342-1350, 2005 ( 0/2005 )
  • Dai Y, Tang J, Zhang JH. Role of Cl- in Cerebral Vascular Tone and Expression of Na+-K+-2Cl- Co-transporter after Neonatal Hypoxia- Ischemia. Canadian Journal of Physiology and Pharmacology, 83:767-773, 2005 ( 0/2005 )
  • Tang J, Fitzgerald SM, Boughtman BN, Cole SW, Brands MW, Zhang JH. Decreased RhoA Expression in Myocardium of Diabetic Rats. Canadian Journal of Physiology and Pharmacology, 83:775-783, 2005 ( 0/2005 )
  • Park S, Zhou C, Tang J, Colohan A, J.H. Zhang JH. Apoptosis and Subarachnoid Hemorrhage. Pharmacology of Cerebral Ischemia. Ed. J. Krieglstein, S. Klumpp. p217-227, 2004 ( 0/2004 )
  • Park S, Yamaguchi M, Zhou C, Calvert JW, Tang J, Zhang JH. Neurovascular protection reduces early brain injury after subarachnoid hemorrhage. Stroke  35(10):2412-2417, 2004 ( 0/2004 )
  • Kusaka I, Kusaka G, Zhou C, Ishikawa M, Nanda A, Granger DN, Zhang JH &  Tang J. Role of AT1 Receptors and NAD(P)H Oxidase in Diabetes-Aggravated Ischemic Brain Injury. Am J Physiol Heart Circ Physiol 286(6):H2442-51, 2004 ( 0/2004 )
  • Tang J, Liu J, Zhou C, Alexander S, Nanda A, Granger DN, Zhang JH. Deficiency of Metalloproteinase-9 Gene Enhances Brain Injury caused by Collagenase-Induced Intracerebral Hemorrhage. J Cereb Blood Flow Metab. 24:1133-1145, 2004 ( 0/2004 )
  • Massey AR, Miao L, Smith BN, Liu J, Kusaka I, Zhang J, Tang J. Increased RhoA translocation in renal cortex of diabetic rats. Life Sciences 9350:1-10, 2003 ( 0/2003 )
  • Akin E, Clower B, Tibbs R, Tang J, Zhang J. Bilirubin produces apoptosis in cultured bovine brain endothelial cells. Brain Res 931:168-175, 2002 ( 0/2002 )
  • Satoh M, Perkins E, Kimura H, Tang J, Chun Y, Heistad DD, Zhang JH. Posttreatment with adenovirus-mediated gene transfer of calcitonin gene-related peptide to reverse cerebral vasospasm in dogs. J Neurosurg 97:136-42, 2002 ( 0/2002 )
  • Miao L, Calvert J, Tang J & Zhang J. Rho-A and Rho-kinase in Cerebral Arteries in Diabetic Rats. Life Sci 71: 1175-1185, 2002 ( 0/2002 )
  • Yin W, Tibbs R, Tang J, Badr A & Zhang J. Haemoglobin and ATP levels in CSF from a dog model of vasospasm. J Clin Neurosci 9:425-428, 2002 ( 0/2002 )
  • Miao L, Calvert J, Tang J, Parent A & Zhang J. Age‑related Rho‑A expression in Blood Vessels of Rats. Mechanism of Aging and Development 122: 1757-1770, 2001 ( 0/2001 - 0/2002 )
  • Miao L, Tang J, Esposito D & Zhang J. Age‑related Changes of P2 Receptor mRNA of Rat Cerebral Arteries. Exp Gerontol 37: 67-79, 2001 ( 0/2001 )
  • Tang J, Neidigh J, Cooksey R & McClain D. Transgenic mice with increased hexosamine flux specifically targeted to beta-cells exhibit hyperinsulinemia and peripheral insulin resistance. Diabetes 49: 1492-6, 2000 ( 0/2000 )
  • Tang J & Zhang J. Mechanisms of [Ca2+] elevation by H2O2 in islets of rats. Life Sciences 68:475-481, 2000 ( 0/2000 )
  • Veerababu G, Tang J, Hoffman R, Daniels M, Hebert L, Crook E, Cooksey R & McClain D. Overexpression of glutamine: fructose-6-phosphate amidotransferase in the liver of transgenic mice results in enhanced glycogen storage, hyperlipidemia, obesity, and impaired glucose tolerance. Diabetes 49: 2070-2078, 2000.   ( 0/2000 )
  • Tang J, Feng G & Li W. Induced direct binding of adapter protein NCK to the GTPase-activating protein (GAP)-associated protein p62 by epidermal growth factor. Oncogene 15: 1823-1832, 1997 ( 0/1997 )
  • She HY, Rockow S, Tang J, Nishimura R, Skolnik EY, Chen M, Margolis B & Li W. Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptors in living cells. Mol Biol Cell 8: 1709-1721, 1997 ( 0/1997 )
  • Roe MW, Worley JF, Tokuyama Y, Philipson LH, Sturis J, Tang J, Dukes ID, Bell GI & Polonsky KS. Non-insulin-dependent diabetes mellitus is associated with loss of pancreatic b-cell L-type Ca2+ channel activity. Am J Physiol 270: E133-140, 1996 ( 0/1996 )
  • Tang J, Pugh W, Polonsky K & Zhang H. Preservation of Insulin Secretory responses to P2-purinoceptor agonists in Zucker diabetic fatty rats. Am J Physiol 270: 270: E504-E512, 1996 ( 0/1996 )
  • Rockow S, Tang J, Xiong W & Li W. Nck inhibits NGF and basic FGF induced PC12 cell differentiation via mitogen-activated protein kinase-independent pathway. Oncogen 12: 2351-2359, 1996 ( 0/1996 )
  • Macdonald MJ, Tang J & Polonsky KS. Low mitochondrial glycerol phosphate dehydrogenase and pyruvate cardoxylase in pancreatic islets of Zucker diabetic fatty rats. Diabetes 45: 1626-1630, 1996 ( 0/1996 )
  • Sturis J, Pugh WL, Tang J & Polonsky KS. Prevention of diabetes does not completely prevent insulin secretory defects in the ZDF rat. Am J Physiol 269: E786-E792, 1995 ( 0/1995 )
  • Tokuyama Y, Sturis J, Depaoli A, Takeda J, Stoffel M, Tang J, Sun X, Polonsky K & Bell G. Evolution of b-cell dysfunction in the male Zucker diabetic fatty rat. Diabetes 44: 1447-1457, 1995 ( 0/1995 )
  • Sturis J, Pugh WL, Tang J, Ostrega DM, Polonsky JS & Polonsky KS. Alterations in pulsatile insulin secretion in the Zucker diabetic fatty rat. Am J Physiol 267: E250-E259, 1994 ( 0/1994 )
  • Ryan EA, Tobin BW, Tang J & Finegood DT. A new model for the study of mild diabetes during pregnancy. Diabetes 42: 316-323, 1993 ( 0/1993 )
  Scholarly Journals--Accepted
  • Souvenir R, Fathali N, Ostrowski R, Lekic T, Zhang JH, Tang J. Tissue Inhibitor of Matrix Metalloproteinase Mediates Erythropoietin-induced Neuroprotection in Hypoxia Ischemia. Neurobiology of Disease. In press   ( 0/2011 )
  • Chen H, Burris M, Fajilan A, Spagnoli F, Zhang JH, Tang J. Prolonged Exposure to Isoflurane Ameliorates Infarction Severity in the Rat Pup Model of Neonatal Hypoxia-Ischemia. Translational Stroke Research. In press ( 0/2011 )
  • Ma Q, Huang B, Khatibi N, Rolland W, Suzuki H, Zhang JH and Tang J. PDGFR-α Inhibition Preserves Blood-Brain Barrier after Intracerebral Hemorrhage. Annals of Neurology. In press ( 0/2011 )