Wolff Kirsch, MD Professor, Neurosurgery School of Medicine Professor, Basic Sciences School of Medicine Member, Biochemistry, SM, Faculty of Graduate Studies

Research & Grantsmanship 

  Funded Research Project (PI)

• Protocol 54174 ( 3/2000 - 12/2009 )

• Protocol 51232 ( 7/2005 - 6/2009 )

• Protocol 85045. ( 9/2006 - 9/2007 )

• Protocol 84035. ( 5/2006 - 5/2007 )

• Protocol 53094. ( 5/2006 - 5/2007 )

• Protocol 83050 ( 11/2004 - 11/2005 )

• Protocol 83028 ( 8/2004 - 8/2005 )

• Protocol 54174 ( 7/2004 - 6/2005 )

• Protocol 84035 ( 6/2004 - 6/2005 )

• Protocol 40052 ( 3/2000 - 6/2005 )

• Protocol 53094 ( 5/2004 - 5/2005 )

  Funded Research Project (CI)

• Laparoscopic hemostatic device; PI Yong Hua Zhu, M.D. ( 6/2006 - 7/2007 )

• Femoral artery puncture wound closure device; PI Yong Hua Zhu, M.D. ( 6/2006 - 7/2007 )

• Modified chitosan production; PI Yong Hua Zhu, M.D. ( 5/2005 - 7/2007 )

• Ligating clip ( 7/2004 - 6/2005 )

• Closure device ( 7/2004 - 6/2005 )

• Drug delivery system catheter ( 7/2004 - 6/2005 )

• Retractor ( 7/2004 - 6/2005 )

• Wound locator ( 7/2004 - 6/2005 )

• Trocar facilitator ( 7/2004 - 6/2005 )

• Chitosan fabric ( 7/2004 - 6/2005 )

• Chitosan puff ( 7/2004 - 6/2005 )

• Mechanism for parturition ( 7/2004 - 6/2005 )

• Hemostatic sponge ( 7/2004 - 6/2005 )

• Adhesive development ( 7/2004 - 6/2005 )

  Abstracts Reporting Research -- Peer Reviewed

• Hong S, Mueller C, Magaki S, Petersen F, Kirsch WM. "Apoliprotein E genotype frequences in a prospective study of sporadic late onset dementia." Journal of Investigative Medicine 55.1 (2007): S99. ( 1/2007 )

• Mueller C, Magaki S, Kirsch WM.. "Assessment of altered blood/brain iron metabolism as a risk factor for the development of Alzheimer's Disease." Alzheimer's & Dementia. The Journal of the Alzheimer's Association 2.3 Suppl 1 (2006): S483-. ( 7/2006 )

• Magaki S, Kelln W, Mueller C, Raghavan R, Jeong J, Woods K, Oberg K, Tourtellotte W, Vinters H, Kirsch W. "Immunohistochemical localization of iron regulatory protein-2 in Alzheimer's Disease hippocampus." Alzheimer's & Dementia. The Journal of the Alzheimer's Association 2.3 Suppl 1 (2006): S430-. ( 7/2006 )

• Mueller C, Bartnik BL, Patra S, Baqai W, Petersen F, Holshouser BA, Kirsch WM. "Analysis of metabolite levels and ratios in age matched controls, mild cognitive impairment, and Alzheimer's Disease converters using 1H magnetic resonance spectroscopy." Alzheimer's & Dementia. The Journal of the Alzheimer's Association 2.3 Suppl 1 (2006): S344-. ( 7/2006 )

• Magaki S, Mueller C, Dickson C, Kirsch W. "Increased levels of proinflammatory cytokines in mild cognitive impairment compared to healthy aged controls." Alzheimer's & Dementia. The Journal of the Alzheimer's Association 2.3 Suppl 1 (2006): S139-. ( 7/2006 )

• Britt III W, Bhaskerrao S, Petersen F, Baqai W, Larsen J, Dickson C, Kirsch WM. "The architecture of mild cognitive impairment: A preliminary study." Alzheimer's & Dementia. The Journal of the Alzheimer's Association 2.3 Suppl 1 (2006): S297-. ( 7/2006 )

• Kirsch WM, Petersen F, Ayaz M, Khan A, Kim I, Baqai W, Dickson C, Holshouser BA, Oyoyo U, Kido D, Haacke EM. "Altered brain iron metabolism as a risk factor for Alzheimer's Disease." Alzheimer's & Dementia. The Journal of the Alzheimer's Association 2.3 Suppl 1 (2006): S338-. ( 7/2006 )

• Oyoyo U, Yi A, Cruise R, Barros D, Dickson C, Dickson A, Larsen J, Kido D, Kirsch W.. "Hippocampal subsegmentation versus traditional total volumetric measurements in early detection of patients with Alzheimer's Disease (AD).." Alzheimer's & Dementia. 1.1 (2005): S35-S36. ( 6/2005 )

• Snissarenko E, Chin V, Anton L, Kim I, Haacke EM, Ayaz M, Khan A, Chong S, Obenaus A, Kido D, Kirsch WM.. "Imaging and quantifications of brain iron based on magnetic resonance susceptibility.." Journal of Investigative Medicine 53.1 (2005): -. ( 1/2005 )

• Chin V, Snissarenko E, Anton L, Kim I, Mueller C, Magaki S, Obenaus A, Kirsch WM.. "Isolation of discrete regions of the brain from iron regulatory protein-2 knockout mice.." Journal of Investigative Medicine 53.1 (2005): -. ( 1/2005 )

• Khan A, Ayaz M, Haacke E, Kirsch W, Kido D.. "Correlating phase with iron content in Alzheimer's disease.." Proc. Intl. Soc. Mag. Reson. Med. 13. (2005): 1186-1186. ( 1/2005 )

• Mueller C, Coon K, Magaki S, Snissarenko E, Chin V, Kirsch W.. "Is altered blood/brain iron metabolism a risk factor for the development of Alzheimer's disease?." The Seventh Annual Research Symposium . (2004): -B-15. ( 9/2004 )

• Kirsch WM, Collins D, Larsen J, Kido D, Holshouser B, Obenaus A, Britt W, Petersen F, Coon K, Haacke EM. "Iron metabolism alterations in Alzheimer's disease.." Proceedings book; 4th Annual BRP Grantee Meeting . (2004): -. ( 7/2004 )

• Haacke EM, Ayaz M, Boikov AS, Krishnamurthy B, Manova ES, Dickson A, Dickson C, Baqai W, Britt W, Kirsch W, Kido D, Petersen F.. "Is a progressive increase in the number of microhemorrhages in the aged an earlier sign of Alzheimer's disease?." ISMRM . (): -. (*)