Xiao Mao, MD Asst Res Prof, Radiation Medicine School of Medicine

Research & Grantsmanship 

  Funded Research Project (PI)

• Stereological quantitative study of dose response of rat retina and choroids following proton and Iron-56 irradiation ( 7/2007 - 6/2010 )

• Quantitative evaluation of AEOl10113 on radiation in brain tumor vasculature model ( 9/2006 - 7/2007 )

• Cell loss in radiated retina: correlation with doses ( 5/2007 )

• Three-dimensional analysis and visualization of rat brain capillary network ( 4/2007 )

• To Study DNA double strand breaks following irradiation on a proliferative retinal microvessel model ( 7/2004 - 6/2005 )

  Funded Research Project (CI)

• Confocal Laser Scanning Computer Assisted Stereology to quantify (PI Archambeau) ( 7/2007 - 6/2010 )

• Progressive Alterations of Central Nervous System Structure and Function Are Caused by Charged Particle Radiation(PI: Greg Nelson) ( 6/2005 - 12/2008 )

• Quantification of the Dose Response of Microvessel Parameters in the Retina, the Brain Cortex, and White Matter Following Iron-56 and Proton Irradiation. (PI: John Archambeau) ( 7/2004 - 6/2008 )

• Determination of the capability of the radiation protector, manganic porphyrin, to protect the rectal mucosa of the rat from late radiation population changes(PI: John Archambeau) ( 1/2006 - 12/2007 )

• Preclinical Development of Metalloporphyrin Antioxidant Mimetic for Prostate Cancer Therapy ( 5/2007 )

• Quantification of the Dose Response of Microvessel Parameters in the Retina, the Brain Cortex, and White Matter Following Iron-56 and Proton Irradiation(PI: John Archambeau) ( 7/2005 - Present )

  Grant Proposals--Funded

• Radiation-induced oxidative stress in retinal degeneration and radioprotective effect of a metalloporphyrin compound in rat retinal model ( 2/2009 - 2/2010 )

  Grant Proposals--Submitted

• Quantitative evaluation of a metalloporphyrin antioxidant wiht proton radaition in a glioblastoma model ( 11/2008 - 10/2010 )

• Mechanism in stress response of low dose ionizing radiation in a mouse skin model-NIH ( 10/2009 - 9/2010 )

  Abstracts Reporting Research -- Peer Reviewed

• 34. Jeff Kao, Xiao Wen Mao, Andy Obenaus, Sheng-Kwei Song.. "Radiation induced injury of the lens and retina in rat eyes: Assessment with diffusion tensor imaging." ISMRM 14th Scientific Meeting . (2006): -. ( 4/2006 )

• Xiao Wen Mao. "Charged particle irradiation causes a progressive loss of cells and a remodeling of CNS tissue as a function of dose, time and LET:A Progress report." 4ISWRR . (2006): -. ( 1/2006 )

• Mao XW, Archambeau P, Baqai W, Larsen S and Archambeau J. "A quantification study of brain vasculature to iron irradiation using stereology." 53th Annual Meeting of Radiation Research Society, Denver, 2005 . (2005): -. ( 11/2005 )

• 37. Mao XW, Archambeau JO, Archambeau P, Mekonnen T, and Larsen S,. "Stereological analysis of dose response of microvessel parameter in brain to iron and Proton Irradiation: a progress report." Radiation Research . (1969): -. (*)

• Mao XW, Archambeau JO, Archambeau P, Mekonnen T, and Larsen S, . "Stereological analysis of dose response of microvessel parameter in brain to iron and Proton Irradiation: a progress report.." Radiation Research society . (): -. (*)

• Xiao Wen Mao, Tsehay Mekonnen, James Crapo and John Archambeau.. "Effect of metalloporphyrin antioxidant on endothelial cells following irradiation." Cancer Research . (): -. (*)

• 40. Xiao Wen Mao, Tsehay Mekonnen, James Crapo and John Archambeau. "Effect of metalloporphyrin antioxidant to reduce the radiation population damage in rat retinal following proton irradiation: A pilot study." Radiation Research . (): -. (*)

• 41. X.W. Mao, L. Kubinova, J. Janacek, T. Mekonnen, N. Lindsay and J.O. Archambeau. "Dose Response of Brain Vasculature to Proton Irradiation: a Progress Report." NASA workshop . (): -. (*)

• 42. Xiao Wen Mao, Cecile Favre, Michael J. Pecaut, and Greg Nelson. "Stereological Quantification of Rat Brain Vascular Population Following Iron Ion Radiation: a Progress Report. ." NASA workshop . (): -. (*)